The Science of Sleep: Melatonin, GABA receptors and more with Prof. Ulf Ellervik

In our fast-paced world, sleep often takes a backseat to our busy schedules. But what exactly is it and what compounds help us fall asleep or keep awake? In the latest episode of our podcast, we talked with Ulf Ellervik, a Swedish professor of bio-organic chemistry at Lund University and the author of 'The Science of Sleep.'  As we explore the various stages of sleep – light sleep, deep sleep, and REM sleep – Ulf explains how each phase plays a vital role in our overall health. For instance, deep sleep is essential for physical recovery, while REM sleep is crucial for memory consolidation and creativity. One of the most intriguing aspects of the discussion is the impact of modern inventions on our sleep patterns (also part of our usual pub quiz question!). Ulf notes that today, we sleep on average around two hours less than we did a hundred years ago – a figure widely cited in sleep research, though not without debate among some scientists. Caffeine, a common go-to for many, is also discussed in detail. Ulf explains how caffeine blocks adenosine receptors, which are responsible for making us feel sleepy. While it can provide a temporary boost in alertness, it does not alleviate sleep pressure. This means that while we may feel awake, our bodies still crave rest. The conversation also touches on the importance of understanding our circadian rhythms and the dangers of relying on sleep medications. Ulf Ellervik's insights are not only informative but also serve as a reminder to prioritise our sleep in a world that often encourages us to do more and rest less. Tune in now to discover how you can improve your sleep and overall well-being! USEFUL LINKS More about Ulf Ellervik: https://portal.research.lu.se/en/persons/ulf-ellervik/ Ulf Ellervik's 'Science of Sleep': https://www.amazon.com/Science-Sleep-Ulf-Ellervik/dp/1493093363 Support the show