Jul 20, 2026 · 1 hr 4 min · 10 segments
Dr. Darsh Shah and Dr. Altamash Raja sit down with Dr. Marissa McCarthy, a board-certified physical medicine and rehabilitation physician, brain injury specialist, and residency program director for…
Marissa McCarthyGuest
Altamash RajaHost
Darsh ShahHost
But we're now entering a territory where brain health is becoming a big topic too, and treating some-- an organ that thinks about itself in a way, but also is really new on the frontier aspect of-


What is this common thread that you've been hanging onto, and what is really pulling you forward?

The fact that the brain has the ability to rewire and reroute if we treat it correctly.

There is that opportunity for healing, recovery, prevention of early cognitive decline.

'Cause just beyond brain injury itself, a lot of people will come to me and say, "Am I gonna get Alzheimer's? Am I gonna get some type of frontal lobe dementia because I hit my head one time?" I think that is almost like a fear factor for a lot of people.

And if I can give a shout-out to Dale Bredesen from the UCLA Buck Institute, he wrote The End of Alzheimer, and I read that book probably 15 years ago or so.

And to be honest with you, I feel like that has been my Bible in terms of brain injury recovery, prevention, again, of that early cognitive decline or early onset dementia.

I did have two grandparents who suffered from dementia, and it is an awful way to go, not just for them, but for their family members.

Not being able to recognize my mom and her sister, I think that really takes a toll on people, again, not just the person suffering from it, but really the family surrounding them.

So that was something that I kinda took to heart, and how can we really tackle that and still provide them with a great quality of life? And if you read that book, you'll understand why.

And it's not just about Alzheimer's, it's about a lot of... that you can do to help your, your mind and your brain be a lot more in tune and will age well.

I think a lot of the things that we are all focused on at this point is how long can we stay looking young, acting young, feeling young, and the same thing goes for your brain.

I mean, your muscles aren't gonna function as well if your brain isn't functioning well.

The biggest factor, and I'll tell you this from my perspective, and people make fun of me because I always say I have a love affair with sleep.

They don't understand how I have four kids, I work four jobs, and I still sleep nine hours a night.

But we're now entering a territory where brain health is becoming a big topic too, and treating some-- an organ that thinks about itself in a way, but also is really new on the frontier aspect of-


What is this common thread that you've been hanging onto, and what is really pulling you forward?

The fact that the brain has the ability to rewire and reroute if we treat it correctly.

There is that opportunity for healing, recovery, prevention of early cognitive decline.

'Cause just beyond brain injury itself, a lot of people will come to me and say, "Am I gonna get Alzheimer's? Am I gonna get some type of frontal lobe dementia because I hit my head one time?" I think that is almost like a fear factor for a lot of people.

And if I can give a shout-out to Dale Bredesen from the UCLA Buck Institute, he wrote The End of Alzheimer, and I read that book probably 15 years ago or so.

And to be honest with you, I feel like that has been my Bible in terms of brain injury recovery, prevention, again, of that early cognitive decline or early onset dementia.

I did have two grandparents who suffered from dementia, and it is an awful way to go, not just for them, but for their family members.

Not being able to recognize my mom and her sister, I think that really takes a toll on people, again, not just the person suffering from it, but really the family surrounding them.

So that was something that I kinda took to heart, and how can we really tackle that and still provide them with a great quality of life? And if you read that book, you'll understand why.

And it's not just about Alzheimer's, it's about a lot of... that you can do to help your, your mind and your brain be a lot more in tune and will age well.

I think a lot of the things that we are all focused on at this point is how long can we stay looking young, acting young, feeling young, and the same thing goes for your brain.

I mean, your muscles aren't gonna function as well if your brain isn't functioning well.

The biggest factor, and I'll tell you this from my perspective, and people make fun of me because I always say I have a love affair with sleep.

They don't understand how I have four kids, I work four jobs, and I still sleep nine hours a night.
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