Oct 7, 2026 · 40 min · 11 segments
Send us Fan Mail What happens when the thing making people sick isn’t hiding in the water, the air, or some mysterious chemical… but in their…
Okay, so right when we jump into this episode, Peter gives us a pretty good description of the town and the people at this time.
So I feel like we can let him do the town breakdown for us, can't he?
Yeah, I agree.
[gentle music] Valley Springs, South Dakota, a tiny farming community of about 800 people, not far from the Minnesota border.
It's a community of farms and suburban professionals, many of whom work in the nearby city of Sioux Falls.
People here are accustomed to hard work and the hard weather, and aren't the type to complain.
[laughs] Okay, so I have a question for you before we continue.
Always a great sign.
How many things do you eat, and I mean, like, regularly eat, before you started connecting the dots of what might be causing a mysterious, like, months-long illness?
Okay, so probably a lot of things.
I'd blame first, then it would be the caffeine intake that I have on a daily and then, you know, definitely the amount of stress that I go through on a daily, mostly done by myself.
Yeah, I agree.
I mean, if I was having this, like, months-long illness and no answers, I would immediately go to, "I'm dying."
Mm-hmm.
Um, I actually relate to a survivor that we meet in this episode who was literally put in a mental hospital because doctors thought she was having a nervous breakdown.
The real reason for her symptoms, that is an answer that explains why regulations on our food and believing science is crucial and literally lifesaving.
Totally.
We're also told that this is apparently one of the CDC's most bizarre and baffling outbreaks, and one they literally use to train epidemiologists to this day.
It has a name in medical terms that of course Danielle is gonna make me pronounce, and the name is-
[laughs]
... hamburger, hamburger thyrotoxi- hamburger thyrotoxicosis.
[laughs] Man
I thought I was setting you up there
...
Okay, so right when we jump into this episode, Peter gives us a pretty good description of the town and the people at this time.
So I feel like we can let him do the town breakdown for us, can't he?
Yeah, I agree.
[gentle music] Valley Springs, South Dakota, a tiny farming community of about 800 people, not far from the Minnesota border.
It's a community of farms and suburban professionals, many of whom work in the nearby city of Sioux Falls.
People here are accustomed to hard work and the hard weather, and aren't the type to complain.
[laughs] Okay, so I have a question for you before we continue.
Always a great sign.
How many things do you eat, and I mean, like, regularly eat, before you started connecting the dots of what might be causing a mysterious, like, months-long illness?
Okay, so probably a lot of things.
I'd blame first, then it would be the caffeine intake that I have on a daily and then, you know, definitely the amount of stress that I go through on a daily, mostly done by myself.
Yeah, I agree.
I mean, if I was having this, like, months-long illness and no answers, I would immediately go to, "I'm dying."
Mm-hmm.
Um, I actually relate to a survivor that we meet in this episode who was literally put in a mental hospital because doctors thought she was having a nervous breakdown.
The real reason for her symptoms, that is an answer that explains why regulations on our food and believing science is crucial and literally lifesaving.
Totally.
We're also told that this is apparently one of the CDC's most bizarre and baffling outbreaks, and one they literally use to train epidemiologists to this day.
It has a name in medical terms that of course Danielle is gonna make me pronounce, and the name is-
[laughs]
... hamburger, hamburger thyrotoxi- hamburger thyrotoxicosis.
[laughs] Man
I thought I was setting you up there
...
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