Sep 17, 2026 · 30 min · 9 segments
Ever freaked out about finding 'meaning' in your life? A new study might help you understand where that (uniquely human) feeling comes from. (Note: We published part 1 on June 15, 2025)
Yilin LiuGuestWayne, I hope you, and none of our other listeners out there, are suffering from what I'm gonna be talking about right at the top here.
This is osteoporosis.
Hmm.
If you don't have this or don't have anyone in your family who's had it, you've probably heard of it.
My mom's got it.
Does she?
Yep.
Yeah, this is the gradual weakening of the bones in your body, the, the structure that holds everything together.
Roughly a half billion people on planet Earth will have this at some point in their life.
This is something I think almost all of us can expect to be confronted with.
And yeah, presents most commonly as, like, a, a, a broken wrist, a broken hip.
Uh, and those hip injuries can long-term end up being fatal.
Those are extremely dangerous, and, uh, also to the vertebrae.
Horrible stuff, and that's why I was really excited about a study that shouldn't have done what it did.
It was a Phase 1 trial, and what that means is, in this case, obviously connected to osteoporosis, they're only trying to figure out is this medical intervention that we're thinking about doing, that we want to do, does it hurt the person we're trying it on?
Yeah.
Because you could create a molecule-
Is it safe? Yeah.
Yeah, is it safe for them? And you can up the dosage or lower the dosage, but that's the only thing you're trying to look at with that part of the trial.
And in this case, they saw a lot more, and it was with 10 women, so just, that is a caveat.
This is not a large number of people.
They were between the ages of 50 and 72, and what they did is they extracted bone marrow from their hips.
Mm-hmm.
And then they took that bone marrow out, and they isolated something, I'm gonna refer to them as MSCs.
The technical term, I'm gonna read this, is mesenchymal stem stromal cells.
Wayne, I hope you, and none of our other listeners out there, are suffering from what I'm gonna be talking about right at the top here.
This is osteoporosis.
Hmm.
If you don't have this or don't have anyone in your family who's had it, you've probably heard of it.
My mom's got it.
Does she?
Yep.
Yeah, this is the gradual weakening of the bones in your body, the, the structure that holds everything together.
Roughly a half billion people on planet Earth will have this at some point in their life.
This is something I think almost all of us can expect to be confronted with.
And yeah, presents most commonly as, like, a, a, a broken wrist, a broken hip.
Uh, and those hip injuries can long-term end up being fatal.
Those are extremely dangerous, and, uh, also to the vertebrae.
Horrible stuff, and that's why I was really excited about a study that shouldn't have done what it did.
It was a Phase 1 trial, and what that means is, in this case, obviously connected to osteoporosis, they're only trying to figure out is this medical intervention that we're thinking about doing, that we want to do, does it hurt the person we're trying it on?
Yeah.
Because you could create a molecule-
Is it safe? Yeah.
Yeah, is it safe for them? And you can up the dosage or lower the dosage, but that's the only thing you're trying to look at with that part of the trial.
And in this case, they saw a lot more, and it was with 10 women, so just, that is a caveat.
This is not a large number of people.
They were between the ages of 50 and 72, and what they did is they extracted bone marrow from their hips.
Mm-hmm.
And then they took that bone marrow out, and they isolated something, I'm gonna refer to them as MSCs.
The technical term, I'm gonna read this, is mesenchymal stem stromal cells.
The rest of this transcript — segmented and speaker-labeled, so you land on the exact moment something was said
Search every transcript — by keyword, by phrase, or by meaning, across every show Radar indexes
Trends — what is surging across podcasts, measured against its own baseline
Alerts — when a name you follow appears in a newly indexed episode
No account is needed to search Radar.