Oct 6, 2026 · 49 min · 17 segments
A conversation with best-selling author Mary Roach. Her latest book, 'Replaceable You: Adventures in Human Anatomy,' is part medical history, part investigative travelogue, part unflinching look at…
By the end of the book, Mary, you, you go looking for one simple body part, uh, that science has actually managed to fully replicate.
We've been talking about a lot that, you know, uh, have years and years of, of research ahead of them.
What did you find about that simple body part that science is now able to fully replicate?
Uh, you know what? The best transplant, the best one, uh, that I c- [laughs] I could find, the be- uh, is the fecal microbiome transplant, and that is simply to take the microbiome, the bacteria of a healthy person's intestines, colon, and put it into somebody who has a C.
diff infection, which is a sometimes lethal overgrowth of this bacteria C. difficile.
Um, uh, i- in theory it would be cheap if you just took the fecal material, which is what they used to do.
You know, taking a healthy person's poop and putting it in, or the, you know, you're after the bacteria, not the whole poop.
The other one that I, um, I thought, and I, I, I was starting to think what is, is there anything that science has come up with that is as good, 100% as good as what we started out with, what nature gave us? And I thought, what about tears? That seems pretty simple.
And I got on the phone with this guy from a company called TearLab, and we talked for two rounds of the 45-minute free Zoom, 'cause I'm too cheap to pay for Zoom.
So we, uh, 90 minutes talking about the tear film, not the stuff that you cry, but the material that keeps your eye safe, lubricated, infection-free.
By the end of the book, Mary, you, you go looking for one simple body part, uh, that science has actually managed to fully replicate.
We've been talking about a lot that, you know, uh, have years and years of, of research ahead of them.
What did you find about that simple body part that science is now able to fully replicate?
Uh, you know what? The best transplant, the best one, uh, that I c- [laughs] I could find, the be- uh, is the fecal microbiome transplant, and that is simply to take the microbiome, the bacteria of a healthy person's intestines, colon, and put it into somebody who has a C.
diff infection, which is a sometimes lethal overgrowth of this bacteria C. difficile.
Um, uh, i- in theory it would be cheap if you just took the fecal material, which is what they used to do.
You know, taking a healthy person's poop and putting it in, or the, you know, you're after the bacteria, not the whole poop.
The other one that I, um, I thought, and I, I, I was starting to think what is, is there anything that science has come up with that is as good, 100% as good as what we started out with, what nature gave us? And I thought, what about tears? That seems pretty simple.
And I got on the phone with this guy from a company called TearLab, and we talked for two rounds of the 45-minute free Zoom, 'cause I'm too cheap to pay for Zoom.
So we, uh, 90 minutes talking about the tear film, not the stuff that you cry, but the material that keeps your eye safe, lubricated, infection-free.
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