chronic obstructive pulmonary disease

We had about 20,000 people and 19 different diseases for just healthy aging cohorts and then interventions like yours, caloric restriction and therapeutic plasma is something that was done in the U.S. And we see that these changes in our biomarker would happen with all of these different diseases.

And that's from COPD to diabetes to cardiovascular disease to all different autoimmune diseases.

And in some cases where we had the data where we have patients who are healthy, and then we track them until they develop disease.

For example, with Crohn's disease, we see these changes six years prior to a diagnosis.

And suddenly, a disease that affects roughly half a million Americans has entered a new era.

Our guest today is Dr. Gregory Tino, Associate Professor of Medicine at the Perelman School of Medicine at the University of Pennsylvania, Chief of the Department of Medicine at Penn Presbyterian Medical Center, Principal Investigator for the COPD Foundation's Bronchiectasis and MTM Research Registry, co-author and the International Consensus Recommendations for Bronchiectasis Diagnosis, and newly elected Treasurer of the American Thoracic Society.

If there's anyone who can walk us through where bronchiectasis stands right now and where it's going, it's Dr. Tino.

Welcome to the show and let's get into it.

So I think we're picking it up more now.

for other indications for patients who have underlying symptoms.

Number two, it was often diagnosed as a different condition, whether it was COPD, whether it was chronic bronchitis.

And so people just didn't know how to approach it, how to work it up.

Yeah, so whereas in younger babies, we see that small airway constriction and kind of like a wheezing respiratory distress type picture, it can actually look quite a bit different in older people and usually presents with signs of pneumonia, as well as that significant difficulty breathing as well.

In adults who have underlying lung disease like asthma or COPD, it can cause flare-ups of these diseases, and it can also destabilize underlying medical conditions like heart disease as well.

Yeah, definitely.

I also see it with my diabetic patients as well who are at higher risk.

And so are you noticing that somebody who might, you might not even have lung disease, are you seeing some issues when they come in with respiratory diseases as well?

For sure.

So somebody who might certainly the asthma and the COPD or emphysema, often people people refer to, they're definitely at a higher risk of the significant effect of something that starts out as a mild cold like symptom progresses to a pneumonia.

But anybody who's had a previous heart attack, if they have CHF or congestive heart failure, diabetes, like I mentioned, they can progress faster and have more severe symptoms.

Same thing with lungs.

All your asthma, COPD, you've got nerve rings through the lungs.

Breathing is a neurological event.

I did extensive research and heard from several people that this is the only proper way to heal and get off insulin.

The right armpit sweats.

That right breast is more swollen.

And honestly, most of the lung issues of asthma and CF are also in the upper right lung.

Well, then you know that's that right kidney.

tank.

I do know somebody with COPD, that's respiratory illness, and they will not, cannot even think of stepping outside when the air quality is very poor.

And there's a lot of people in that category in Ennis.

So what do we start to do? I've read a number of reports that have made a determination that perhaps even burning smokeless fuels can be in a situation where, as Alan has described, where the poor air, the smoke sits on the ground close to where people are breathing.

No, honestly, my old boss used to call me CRPD.

and he'd be looking he'd be eating a bowl of porridge at like half seven in the morning I'd be outside hooving a cigarette into me and he'd just be looking at me and eating and then I'd walk in and he goes you alright COPD and then I was off him for like a month he was delighted and then he caught me having a sticky smoke he was like why are you you can't do that when you're a doctor

You can, they all do.

I know.

done even more than, it's even more than like an aesthetic peptide.

There's studies that show that it can help with patients with COPD, potential cancers, including colon cancer.

So there's a lot of like systemic health benefits that go beyond aesthetics for GHKACU copper peptide.

And I really, because I realized there was nobody really presenting this information.

You know, LDN, if you went to the Stanford Long Haul Clinic, the first thing they'd put you on was LDN, a medicine we've been using for decades.

many many years for a lot of different things so those are the things you also want to make sure if you have an acute case of COVID right now well one one be reassured this is a much less virulent strain so you should do fine unless you're compromised with some other things like COPD, asthma, diabetes, morbid obesity, those type of things, heart disease, maybe even an autoimmune disease.

But so the other thing we used, believe it or not, everybody I put during COVID on ivermectin, I put on a Z-Pak as well.

And, you know, because you could have a bacterial superinfection.

Yeah, so my parents both passed away.

Physically, they passed away from COPD.

If you're not familiar, it's basically your lungs slowly lose their ability to work over time.

But