Jun 22, 2026 · 48 min · 12 segments
This week I interviewed Dr. Adrijana Kekic! She is the founder of Futurama, which applies integrated genetic, metabolic, and molecular analysis to individuals who look…
Brian GrynHost
And, and, you know, you talk about like cellular drift, um, as like dysfunction that progressively like progresses silently while your standard labs can look normal, like what's actually happening biologically, uh, in that, you know, during that window that, you know, can go undetected, um, and it can become a real clinical problem.
So how long, I'm going to start from the bottom and work my way up to that question.
How long can cellular drift, which I will explain what it is, how long can cellular drift happen before you end up with say, like I did, God forbid, or with certain diagnosis? The short answer is it depends, but usually this is something that takes time.
So typically it's either months or years before you end up with a significant disease or disorder.
A case in point would be when you go do your standard lab testing, and I assume both of us here have done numerous physical, you know, yearly physical exam.
So typically when you do your physical exam, do you have any labs done during that time, Brian?
And hopefully that lab work is indeed comprehensive, which it seems like or sounds like it is.
But usually for most of us, when you go do your labs or physical lab, yearly physical, you will get about, I don't know, 20 to maybe 50 biomarkers that we look at.
So, you know, things related to your blood sugar, your blood chemistry, lipids, maybe thyroid hormones or hormones, inflammation, and so on.
So when you do the standard testing, we are only skimming the surface in terms of what's really happening at the cellular level.
Why? Because we're really not operating from this place of so-called multi-omics approach to health.
What does that mean? Multi-omics approach to health is really systems thinking applied to biology so it's called system biology approach to health uh well let me just really quickly pause on that and kind of open that up so what is that you have heard of genetic testing or maybe you had your genetic testing done
um yes i have yeah okay just yeah certain gene snips you know not like um but anyways go ahead
So you had certain genes looked at, which is, I think, what most of us who have had genetic testing would say, oh yeah, I had a genetic test done.
And maybe I checked if I have MTHFR mutation, methyl and tetrahydrofolate enzyme gene that encodes for that enzyme mutation, or maybe you did genetic testing related to your predisposition to cancers, for example.
And, and, you know, you talk about like cellular drift, um, as like dysfunction that progressively like progresses silently while your standard labs can look normal, like what's actually happening biologically, uh, in that, you know, during that window that, you know, can go undetected, um, and it can become a real clinical problem.
So how long, I'm going to start from the bottom and work my way up to that question.
How long can cellular drift, which I will explain what it is, how long can cellular drift happen before you end up with say, like I did, God forbid, or with certain diagnosis? The short answer is it depends, but usually this is something that takes time.
So typically it's either months or years before you end up with a significant disease or disorder.
A case in point would be when you go do your standard lab testing, and I assume both of us here have done numerous physical, you know, yearly physical exam.
So typically when you do your physical exam, do you have any labs done during that time, Brian?
And hopefully that lab work is indeed comprehensive, which it seems like or sounds like it is.
But usually for most of us, when you go do your labs or physical lab, yearly physical, you will get about, I don't know, 20 to maybe 50 biomarkers that we look at.
So, you know, things related to your blood sugar, your blood chemistry, lipids, maybe thyroid hormones or hormones, inflammation, and so on.
So when you do the standard testing, we are only skimming the surface in terms of what's really happening at the cellular level.
Why? Because we're really not operating from this place of so-called multi-omics approach to health.
What does that mean? Multi-omics approach to health is really systems thinking applied to biology so it's called system biology approach to health uh well let me just really quickly pause on that and kind of open that up so what is that you have heard of genetic testing or maybe you had your genetic testing done
um yes i have yeah okay just yeah certain gene snips you know not like um but anyways go ahead
So you had certain genes looked at, which is, I think, what most of us who have had genetic testing would say, oh yeah, I had a genetic test done.
And maybe I checked if I have MTHFR mutation, methyl and tetrahydrofolate enzyme gene that encodes for that enzyme mutation, or maybe you did genetic testing related to your predisposition to cancers, for example.
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