Polyunsaturated fat
73
MENTIONS
31
EPISODES
22
PODCASTS
Search complete. 73 mentions across 31 episodes found for "Polyunsaturated fat".
Nov 13, 2026
Peter OsborneHOST
I measure this in everyone that comes into my clinic and this is really quite average 16 to 1 ratio.
Peter OsborneHOST
But you can see here painful neuropathy induced by a diet high in omega-6 PUFAs High omega-6 diets induced neuropathic pain can be blunted by replacement with a diet high in omega-3 PUFAs.
Peter OsborneHOST
And this is the concept that I discussed in depth in my book, No Grain, No Pain.
Peter OsborneHOST
If you haven't read it, read it, follow it.
Lisa BassHOST
And so it just doesn't make sense practically to worry about that, to worry about PFAs.
Lisa BassHOST
Regarding the PFAs, and I think PFAs are like, are we talking about oils or that's PUFAs? polyunsaturated fatty acids.
Lisa BassHOST
I don't know.
Lisa BassHOST
So I think that's what you're talking about there.
Sandy JollesHOST
It passes through you.
Sandy JollesHOST
That is not the case with a lot of forever chemicals, fluoride, PUFAs.
Sandy JollesHOST
They are not transient.
Sandy JollesHOST
Their half-life is fairly long, actually.
15 MINS LATER
Sandy JollesHOST
Maybe they have little ones or considering getting pregnant.
Sandy JollesHOST
And tell me what you want to hear next.
Sandy JollesHOST
Maybe about PUFAs, phthalates, detox products.
Sandy JollesHOST
I'm an open book and I love hearing from you.
Gil CarvalhoHOST
one one specific argument or question i've heard regarding sydney is that the this likelihood of the trans fats is not very believable because the the level of total cholesterol serum cholesterol or ldl cholesterol i forget which one they measured came down by 20 points or so and so the argument is that if if the if they were replacing if the comparator were was trans fats you would expect an increase in total cholesterol to what extent is that a valid argument
Kevin MakiGUEST
yeah well you have these competing effects so you have the influence of the unsaturated fatty acids and even if some trans fatty acids came along with it you've got unsaturated fatty acids lowering ldl cholesterol trans fatty acids would tend to have the opposite effect and so the net would depend on the ratio of unsaturated to trans unsaturated fatty acids and So that does bolster the argument that it was mainly unsaturated PUFAs that were being given.
Kevin MakiGUEST
But trans fats have a very strong and linear relationship to cardiovascular risk that's probably partly mediated through effects on lipids, but partly mediated through other effects.
Kevin MakiGUEST
So you know, again, it is just another one of the question marks we have about these trials, and why I am hopeful that we'll see new trials undertaken.
Oliver WerzGUEST
I think these are really innovative products.
Oliver WerzGUEST
Some of these products even contain some, let's call it simple SPMs, like protectants, RBD5, which are only dihydroxylated PUFAs and easier to produce in the body.
Oliver WerzGUEST
I think these are interesting products, but still, I believe that we need activator and an activator of cells in order to perform to challenge the cell to make the final step towards sbm's biosynthetic step which is of course again the 15 locks i think the 15 locks really is something that we need but also as i pointed out the 15 lock the five locks and what we are currently doing is to follow up which of the let's say sequence of biosynthesis is more important is it first the conversion of the puba by the five locks and then by the 15 locks or first the 15 and then the five and it might strongly depend on the cell type that is involved and the enzymes expressed but this is something where these Um, products come into play because they provide the precursors, which 1 of the 2 can produce already.
Oliver WerzGUEST
So we have 1 step already made and just need the 2nd step in the body to be performed.
Chris KnobbeGUEST
and with all the wheat in their diet, it sounds to me they had a nutrient deficient diet.
Chris KnobbeGUEST
So that's the perfect, if you're consuming a lot of omega-6 PUFA and you're nutrient deficient in the fat soluble vitamins, AD and K2, that right there, that's the setup as far as I'm concerned for this disease.
Benjamin QuoUNKNOWN
Do you also suppose that there's a possibility that we just haven't had the availability of diagnosis for cardiovascular disease prior to maybe about 1900, that people were dying from heart issues, it's just that they were not diagnosed or that just wasn't attributed as a cause.
Benjamin QuoUNKNOWN
Do you suppose that that's also a possibility?
Chris KnobbeGUEST
Sometimes you can't even dig it out.
Chris KnobbeGUEST
And...
Chris KnobbeGUEST
So, but personally, and I don't know if I'm answering your question, I want to, but personally, the only mechanism that I am aware of that could drive the destruction of cardiolipin in the inner mitochondrial membrane, which causes loss of the proton gradient, which is what the electron transport chain depends on, is based on the fact that a high PUFA diet causes oxidation of linoleic acid in the cardiolipin.
Chris KnobbeGUEST
And then that oxidation of the linoleic acid means that there's a three-dimensional conformational change in the molecule and or it's replaced by docosahexaenoic acid, DHA, or arachidonic acid, AA.
Dave FeldmanGUEST
I myself am not a fan.
Dave FeldmanGUEST
I don't think bringing up PUFAs in order to bring down your LDL, given what I know up to this point in time, makes me feel comfortable.
Dave FeldmanGUEST
That's just my two cents.
Dave FeldmanGUEST
You can add more insoluble fiber.
LiuHOST
Polyunsaturated fats or PUFA should be five to 10% of our daily calories with emphasis on quality and balance.
LiuHOST
So if you eat a 2000 calorie diet, that works out to 11 to 22 grams of PUFAs in total.
LiuHOST
Now nuts, seeds, flax seeds, walnuts, pumpkin seeds, sesame seeds, sunflower seeds, all serve as a great source of PUFAs.
LiuHOST
So their vegetable oils have some, just like corn and cottonseed, soybean, sunflower.
LiuHOST
They all have some polyunsaturated fats.
Robert CywesGUEST
If you drink alcohol, you're looking at DUIs and liver disease.
Robert CywesGUEST
And if you eat carbohydrates, especially with PUFA, you're looking at inflammation, you're looking at metabolic syndrome, you're looking at obesity, you're looking at diabetes.
Robert CywesGUEST
And folks, especially if you look at our youth, Over the last few years, there's been this unmentionable massive rise in suicide because people are not coping.
Robert CywesGUEST
They don't have the tools or the skills, the emotion management skills to deal with the pressures of being young, the anxiety, the stress, the depression.
Justin MaresGUEST
Yeah, so I think that the average American gets way too much of their caloric intake in the form of what's called polyunsaturated fatty acids, PUFA.
Justin MaresGUEST
So PUFAs are the primary fatty acid found in a lot of seed oils.
Justin MaresGUEST
They're very high in nuts.
Justin MaresGUEST
They're like in everything, basically.
Justin MaresGUEST
And what's key is they actually, these PUFAs will, they make up a lot of the meat concentration in chickens specifically.
Justin MaresGUEST
So chickens have, they're monogastric, they have one stomach.
Justin MaresGUEST
So it means when they eat what they eat, goes directly into their meat tissue, whereas cows have two.
Justin MaresGUEST
And so you have these chickens basically that have the muscle and fat profile of something resembling a seed oil.
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