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Semax

Semax

MedicationWikipedia

Search complete. 42 mentions across 13 episodes found for "Semax".

Sep 15, 2026

Jordan FeigenbaumGUEST
29:07
That happened earlier this year.
Jordan FeigenbaumGUEST
29:08
And then a panel was convened to vote on them, whether to move them to Category 1, which means that compounding pharmacies can work with these drugs like BPC 157, for example, KPV, TB-500, MOTS-c, Semax, a few other ones.
Jordan FeigenbaumGUEST
29:22
It was seven total drugs on this particular panel's vote.
Jordan FeigenbaumGUEST
29:25
There'll be another one in February of 2027, it seems like.
Jeff GrossGUEST
21:07
Then we go into, uh, you know, other things like, uh, brain, uh, health.
Jeff GrossGUEST
21:13
Like we have Selank and Semax-
Natalie TysdalHOST
21:16
Mm
Jeff GrossGUEST
21:16
... uh, for mood and for brain health.
Jeff GrossGUEST
21:18
For cognitive ability, we like Semax.
Jeff GrossGUEST
21:20
For mood stabilization, uh, we like Selank.
Jeff GrossGUEST
21:24
Uh, those have been very helpful.
SteveHOST
18:07
So if it's, uh, if it's last week, you got three more weeks to go and then you can bump up the dose.
SteveHOST
18:15
And your thoughts on nasal peptides, Semax, Selank, uh, delta sleep inducing peptide, how does bioavailability compare to subcutaneous? Uh, do you need more, uh, if using nasal spray comparatively? No, you actually need to use less because if you use Semax and Selank, like I mentioned in the deep dives, if you take it up the nose, just like blow, uh, cocaine that is [laughs] if you're not in the know, now you're in the know, uh, it goes straight into the brain where it acts-- where it's active.
SteveHOST
18:42
Whereas if you go subq, like the bioavailability is, uh, pretty much the same, right? Maybe, uh, intranasally is a little bit less, uh, because it still needs to be absorbed and you could, um, you know, basically, uh, swallow a little bit into, uh, you know, your, your, your throat and then, then you lose, uh, obviously, uh, the potency because it gets broken down in the intestinal tract because you swallow it.
SteveHOST
19:05
So let's say the bioavailability is 70% up the nose, but 70% of the dose goes into the brain.
SteveHOST
19:12
Whereas if you go subq and you inject it, I don't know, in your stomach subcutaneously, then it has to diffuse and spread out, and now it goes to your hands and your feet and your anus and your brain, right? So it diffuses across the body homogeneously, and now you get a much lower concentration in the brain.
SteveHOST
19:32
So a nasal spray of Semax of 250 micrograms might give you the same effect as 500 micrograms subcutaneously.
SteveHOST
19:42
Um, but for that you have to experiment a little bit.
SteveHOST
19:44
And subcutaneously lasts longer because the subcutaneous depot, um, takes some time to absorb and, and kind of metabolize and, and diffuse through the body.
Mohamed PaikaHOST
28:07
Four peptides in this category are worth knowing.
Mohamed PaikaHOST
28:10
Semax.
Mohamed PaikaHOST
28:11
Semax was developed in Russia from a fragment of ACTH, a natural pituitary hormone, modified to survive long enough in the bloodstream to reach the brain intact.
Mohamed PaikaHOST
28:23
It was developed in Russia starting in the 1980s and formally registered as a drug there in 1994.
Mohamed PaikaHOST
28:30
And it's been used clinically for stroke recovery ever since.
Mitra Basu ChillarGUEST
77:51
it? So it itself is a signaling molecule.
Mitra Basu ChillarGUEST
77:55
Like, for example, Cimex.
Mitra Basu ChillarGUEST
77:58
Cimex is the name of a peptide.
Mitra Basu ChillarGUEST
77:59
It's a small molecule.
Mitra Basu ChillarGUEST
78:01
So if that peptide is injected, it's going to give a signal of regeneration to my brain, maybe enhancement of brain dry neurotropic factor.
Mitra Basu ChillarGUEST
78:12
So it gives me a lot of mental energy.
Mitra Basu ChillarGUEST
78:15
So the role of Cimex is to act on my nervous system.
Mitra Basu ChillarGUEST
78:20
VPC, the role of signal is to act on my other tissues, my muscles, my bones, my joints, my tendons.
Will ColeGUEST
54:20
Um, so there's, those have been a big one for me.
Will ColeGUEST
54:24
Uh, Selank and Semax, I've seen great clinically for telehealth patients.
Will ColeGUEST
54:28
I personally haven't used that from a neuroplasticity, uh, brain health, mood standpoint.
Will ColeGUEST
54:35
Epitalon, I like the research around.
John RaymondGUEST
19:12
In other words, they can be manufactured.
John RaymondGUEST
19:15
The six peptides are BPC-157, TB-500, KPV, MOTS-C, Epidylon, and Semax.
John RaymondGUEST
19:25
Now the committee spurned warnings from career FDA scientists that this was premature and that the compounds hadn't been tested adequately either for efficacy or safety.
John RaymondGUEST
19:38
Now the committee did reject one other peptide, but they approved six of them.
John RaymondGUEST
2:49
In other words, they can be manufactured.
John RaymondGUEST
2:52
The six peptides are BPC-157, TB-500, KPV, MOTS-C, Epidylon, and Semax.
John RaymondGUEST
3:02
Now the committee spurned warnings from career FDA scientists that this was premature and that the compounds hadn't been tested adequately either for efficacy or safety.
John RaymondGUEST
3:15
Now the committee did reject one other peptide, but they approved six of them.
Mike BelkowskiHOST
15:33
So that wraps up Selank.
Mike BelkowskiHOST
15:35
So in a nutshell with Semax, it is notorious for, uh, for those biohackers or those trying to improve like mental focus, nootropic effects.
Mike BelkowskiHOST
15:45
Semax is synonymous with improving focus, um, attention span, mood, uh, that type of a thing.
Mike BelkowskiHOST
15:52
Whereas Selank, again, is, um, helping with anxiety, stress, mood, uh, that type of aspect of mental wellness.
Mike BelkowskiHOST
16:02
So one is for like, again, nootropic, another is kind of anti-anxiety, anti-stress.
Mike BelkowskiHOST
16:08
But commonly, these are paired together in intranasal solutions.
Mike BelkowskiHOST
16:13
So it's a Semax-Selank blend.
Mike BelkowskiHOST
16:16
And so the blend is conceptually attractive because the two peptides are complementary rather than redundant.
SteveHOST
38:56
Um, maybe add in HCG, 500 IU three times per week.
SteveHOST
39:00
Maybe add in Semax and oxytocin, and stop watching so much porn, and watch that video about the last and only video you, you need to watch to improve your libido.
SteveHOST
39:12
And watch the video on how to solve post-finasteride syndrome because, well, you took one milligram finasteride six, six months for, uh, two years ago, but is your DHT level still low? All right? Why would you take DHT Inotate or propionate if you don't have a baseline reading? Maybe your testosterone levels are low.
SteveHOST
39:32
Maybe it's allopregnanolone that is low.

3 more episodes mention Semax.

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