SoS 284: Dr. Amy Boddy Explains Microchimerism: How Much of You Is Actually You?

Join us for a conversation with Dr. Amy Boddy, Professor of Anthropology at UC Santa Barbara and head of the Boddy Lab, a human evolutionary biologist whose work asks why cancer varies across the animal kingdom, how pregnancy reshapes the body, and what it means that nearly all of us carry living cells that originated in someone else. In this episode, Amy explains microchimerism, the phenomenon in which foreign cells can invade and persist in our bodies for decades, turning up in the blood, bone marrow, and pancreas; sometimes with a benefit. Amy makes the case that microchimeric cells deserve a central place in how we think about health and inheritance, and in what it means to be an individual when the boundaries of the body prove so porous. ------------------------------ Find the papers mentioned in this episode: Chua, K. J., Quilang, R. C., Sallinger, K., Aktipis, C. A., Arck, P., Bianchi, D. W., Chang, D., Eikmans, M., S Fjeldstad, H. E., Haig, D., Harrington, W. E., Horsnell, W., Jacobsen, D. P., Kanaan, S. B., Khosrotehrani, K., Lambert, N. C., Nelson, J. L., Olsen, M. B., Pan, T. D., . . . Boddy, A. M. (2025). Identifying Key Questions and Challenges in Microchimerism Biology. Advanced Science, 12(48), e14969. https://doi.org/10.1002/advs.202514969 Boddy, A. M., Fortunato, A., Sayres, M. W., & Aktipis, A. (2015). Fetal microchimerism and maternal health: A review and evolutionary analysis of cooperation and conflict beyond the womb. Bioessays, 37(10), 1106. https://doi.org/10.1002/bies.201500059 ------------------------------ Contact Dr. Boddy: boddy@anth.ucsb.edu ------------------------------ Contact the Sausage of Science Podcast and Human Biology Association: Facebook: facebook.com/groups/humanbiologyassociation/, Website: humbio.org Chris Lynn, Host Website: cdlynn.people.ua.edu, E-mail: cdlynn@ua.edu, Twitter:@Chris_Ly Cristina Gildee, Co-Host & Co-Producer Website: cristinagildee.com, E-mail: cgildee@uw.edu