Open Your Eyes with Dr. Kerry Gelb
Sep 6, 2026 · 32 min · 11 segments
In Part 2 of this conversation, Dr. Kerry Gelb and Dr. Derrick DeSilva go deeper into the science of hormone optimization starting with SHBG, the protein that binds testosterone and prevents your body…
Derrick DeSilvaGuest
Kerry GelbHost
And when I sit with a patient, when I say to them, you need to do this, this, and this.
Because I don't want to deal with the complications because you didn't do what I told you to do.
Because what does anastrozole have? It's got a whole other myriad of side effects that now I've got to deal with.
Why do I want to do that when if you do what I tell you to do, you take the DIM and you do what I tell you, you get out, you do the exercise, you take magnesium, you take your vitamin D, it's not going to happen.
I think it's important that people realize that these hormones come from cholesterol.
Cholesterol gets converted to testosterone, and then testosterone goes to estradiol and DHT and two others that we haven't even talked about, but we need the cholesterol to be able to make So how do you square the enemy in the room, the
You know, listen, I wasn't sweating and now you're going to make me sweat, right? I'm a Philly guy.
My office manager's father had some heart issues and the cardiologist is just barreling barreling his testosterone down excuse me his cholesterol down his testosterone is non-existent saw him yesterday saw him yesterday i don't want to get into personal information but i mean You can't make testosterone if your cholesterol is 100.
And when I sit with a patient, when I say to them, you need to do this, this, and this.
Because I don't want to deal with the complications because you didn't do what I told you to do.
Because what does anastrozole have? It's got a whole other myriad of side effects that now I've got to deal with.
Why do I want to do that when if you do what I tell you to do, you take the DIM and you do what I tell you, you get out, you do the exercise, you take magnesium, you take your vitamin D, it's not going to happen.
I think it's important that people realize that these hormones come from cholesterol.
Cholesterol gets converted to testosterone, and then testosterone goes to estradiol and DHT and two others that we haven't even talked about, but we need the cholesterol to be able to make So how do you square the enemy in the room, the
You know, listen, I wasn't sweating and now you're going to make me sweat, right? I'm a Philly guy.
My office manager's father had some heart issues and the cardiologist is just barreling barreling his testosterone down excuse me his cholesterol down his testosterone is non-existent saw him yesterday saw him yesterday i don't want to get into personal information but i mean You can't make testosterone if your cholesterol is 100.
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