Cholesterol

The family's got heart disease.

Cholesterol's 10.6.

Importantly, the triglycerides are two, which I would say is not normal.

He's got a normal level of these other things.

And just one of the many, many studies, Jeff Volek saying that what the diet does better than anything is reduce small-dense LDL and triglycerides.

So here's a 49-year-old woman.

Cholesterol, she went onto the low-carb diet.

Cholesterol went from, she's a typical hyper-responder.

And if you take nothing else on the episode, make sure this part is covered for sure.

The foundation is a fasting lipid panel that includes an ApoB or non-HDL cholesterol, not just your standard HDL and total cholesterol.

It's fasting glucose plus A1C, it's blood pressure and it's waist circumference or waist to height ratio, not BMI alone.

I think BMI is garbage.

And there's some reason for optimism.

In the trial program for or for glipron, the drug improved markers like waist circumference, non-HDL cholesterol, triglycerides, and blood pressure.

And those trials did include participants from Asian countries, including India.

But, and this is a big but, we don't have good data yet, especially on normal weight South Asians with metabolic syndrome.

Unscrambling Myths.

The Truth About Dietary Cholesterol and GMOs.

Remember the days when eggs were the villains of breakfast? Back in 1968, the cholesterol content of eggs had them painted as dietary dangers, with recommendations to limit their intake.

This cautionary stance was grounded in the belief that dietary cholesterol directly influences levels of bad cholesterol, or low-density lipoprotein , which is associated with heart disease.

In women, it comes to the the thickest cells of the ovaries, and that's where it signals testosterone production.

Now, when that happens, and there's a very similar way of it, this testosterone production mechanism is quite similar in men and women, simply because when we have that binding of luteinizing hormone, the binds to the luteinizing hormone receptor, that activation that occurs is basically you're going to have Cholesterol, you know, we think of cholesterol in different ways, but cholesterol, when people often say it's important for hormone production, well, this is a key example.

It's important for the production of testosterone.

So now I don't want to go on a side rant about cholesterol, and I don't want to say that if you have more cholesterol, this process is going to happen more.

you're just gonna go average you know out in public and people will look normal weight like when when this thing gets into every primary care's clinic in the transcend type 2 diabetes trial both doses of red true tide lowered a1c by an average of 2.2 percent compared to 1.8 percent with ozempic at 80 weeks participants taking red true tide lost an average of 44 pounds that's 19.5 percent at 9 milligrams, and 47 pounds, 20.9% of the body weight at 12 milligrams, compared to 20.9 pounds, so only 9.4% of their body weight with Ozempic.

Ritrutide also delivered greater improvements than Ozempic across certain cardiovascular risk factors, including non-HDL cholesterol, triglycerides, and systolic blood pressure.

What were the primary endpoints? At the end of the 80-week head-to-head trial, a change in A1C from average baseline of 8.3%.

Redutrutide at 9 milligrams, down by 2.2%.