Clomifene
MedicationWikipedia
90
MENTIONS
55
EPISODES
52
PODCASTS
Search complete. 90 mentions across 55 episodes found for "Clomifene".
Oct 29, 2026
Mike SimpsonGUEST
I'm gouging my own eyes out, listening to this.
Mike SimpsonGUEST
You know, it's, they told me I could try Clomid for a week.
Mike SimpsonGUEST
And then if I didn't like that and I'm, and I'm like, Oh my God, this.
Mike SimpsonGUEST
So, uh, I knew guys that were already doing it, that had been through training.
Aimee RauppHOST
Yeah.
Aimee RauppHOST
And you start with Clomid or Letrozole, which initially down-regulates the estrogen.
Aimee RauppHOST
So you'll see a little pullback in your estrogen, but then you get a dump.
Aimee RauppHOST
Or you do nothing.
Aimee RauppHOST
You just stay on your estrogen.
Aimee RauppHOST
What
StephanieGUEST
was that? The Letrozole and the Clomid, they scare me because every time I take them, it's just like I'm crashed forever.
Aimee RauppHOST
You step back.
Ashley RoseGUEST
So.
Ashley RoseGUEST
She started us on just Clomid and doing medicated cycles.
Ashley RoseGUEST
Is this like IVF? Excuse my ignorance.
Ashley RoseGUEST
No, good question.
Kela SmithHOST
Is it stress or insulin resistance or PCOS or thyroid dysfunction, nutrient deficiencies, hypothalamic suppression? Finding the root cause is going to change everything.
Kela SmithHOST
So before you do something like Clomid or Letrozole, let's ask the question, why am I not ovulating in the first place? Now, if you're in perimenopause and you're trying to get pregnant, that could be the reason you're not ovulating.
Kela SmithHOST
And that is fairly normal, not to say that we can't help improve ovulation in perimenopause, but if you are pre-perimenopause and you're in your 20s and 30s and you're not ovulating, that's when we need to say, okay, what is going on here? Don't just take Clomid or Letrozole before you actually ask that question.
Kela SmithHOST
Why am I not ovulating in the first place? Sign number two, your luteal phase is too short.
Kela SmithHOST
So your luteal phase is the time between the time you ovulate, so you actually release that egg, until the day before your next cycle starts.
Jamie MasseyHOST
I was still working with my OB at the time.
Jamie MasseyHOST
And I said, I'm thinking Clomid, like we're going to do some serious stuff, right? And she's like, no, Jamie, we're not doing Clomid.
Jamie MasseyHOST
You're ovulating.
Jamie MasseyHOST
No.
MaggieGUEST
And then I had to take, I don't get regular periods.
MaggieGUEST
And I went through a fertility clinic and did Clomid.
MaggieGUEST
So we're tracking my cycles and obviously my follicles, timed intercourse, and I felt pregnant.
MaggieGUEST
So one of the risk factors with any sort of ovulation induction is A risk of multiples, but that risk isn't, you know, like 50% more.
Aisling MooneyGUEST
But the amount of treatments I went through and the amount of clinics I visited and the amount of doctors I talked to all seemed to be lost into that individual moment.
Aisling MooneyGUEST
So I would go through, for example, at the time, the HSE could only prescribe Clomid, which was a maddening thing when I had already found research to say that letrozole was much more effective for people with PCOS or PMOS now.
Aisling MooneyGUEST
And I found myself maddened then.
Aisling MooneyGUEST
And this sort of grew and grew and grew to the point where I was about 14 years and 11 months in trying.
Richard HorowitzGUEST
I was surprised that when men come in in their 20s and 30s with low T and their testosterone is off, For some reason, a lot of the doctors didn't know that Lyme and Bartonella, because of inflammation in the brain, cause low testosterone.
Richard HorowitzGUEST
And I will give them a little bit of Clomid, Clomiphene, 25 milligrams two or three times a week with Arimidex to stop aromatization.
Richard HorowitzGUEST
And I'll get their testosterone from 100 to 600 without beta-HCG, without shots, resetting the hypothalamic pituitary system, getting the hormones back in balance.
Richard HorowitzGUEST
So, you know, I have all of these tricks in the H is for hormone chapter, you know, in any chronic illness, because...
Chris WilliamsonHOST
Would you have any concerns for people being on Clomid for a long amount of time? Is that something that you think shouldn't be used?
Peter AttiaGUEST
I would feel very strongly about people not being on Clomiphene or Clomid for a long period of time for another reason, which is it really increases the production of a sterol called Desmosterol.
Peter AttiaGUEST
And the reason for that, there's a lot of problems with that, including... potentially an increase in the risk of atherosclerosis, increase in the risk of cataracts and things of that nature.
Peter AttiaGUEST
So I think long-term use of clomiphene is probably not a good idea.
speaker_1HOST
Yes.
speaker_1HOST
Medications like clomiphene are commonly used to stimulate the ovaries to release multiple eggs.
speaker_1HOST
Clomiphene is a CIRM, a selective estrogen receptor modulator.
Manaan KarrayHOST
And a drug like that doesn't just stay neatly in the pelvis.
Manaan KarrayHOST
It crosses the blood brain barrier.
45 more episodes mention Clomifene.
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