HemeTalks: Conversations in Hematology Education
Oct 1, 2026 · 28 min · 13 segments
In this episode of *HemeTalks*, we are joined by Ms. Elise Burton, who shares her experience living with paroxysmal nocturnal hemoglobinuria (PNH). Elise describes how her journey began several years…
Vivek PatelHostRonak MistryHost
And I think this is a common thing that we see, is that patients with aplastic anemia commonly do have these PNH clones that can expand over time.
You know, there, there's recent ASH guidance on this, a recent How I Practice article on looking at guidelines for aplastic anemia, and, and one of those is sending for PNH testing.
So it's really, really important, and our listeners in the community, as you hear this, it's really important to keep this in mind, that a PNH clone can be associated with aplastic anemia and can expand potentially years later.
So I know ATG and cyclosporine and, and Promacta and that journey can be a challenging one when it comes to treatment of aplastic anemia.
And, and today, uh, y- you know, that's a whole separate episode or even just talk about that alone, getting ATG.
Let's get back to it," and, and you're anemic again, and you get this diagnosis of PNH.
Can you tell us a little bit about what's going through your head when you get this diagnosis of PNH? And, you know, I'm sure your hematologist explained this to you.
Walk us through what your mindset was when you get a diagnosis of PNH, and how did your hematologist explain this to you?
And I think this is a common thing that we see, is that patients with aplastic anemia commonly do have these PNH clones that can expand over time.
You know, there, there's recent ASH guidance on this, a recent How I Practice article on looking at guidelines for aplastic anemia, and, and one of those is sending for PNH testing.
So it's really, really important, and our listeners in the community, as you hear this, it's really important to keep this in mind, that a PNH clone can be associated with aplastic anemia and can expand potentially years later.
So I know ATG and cyclosporine and, and Promacta and that journey can be a challenging one when it comes to treatment of aplastic anemia.
And, and today, uh, y- you know, that's a whole separate episode or even just talk about that alone, getting ATG.
Let's get back to it," and, and you're anemic again, and you get this diagnosis of PNH.
Can you tell us a little bit about what's going through your head when you get this diagnosis of PNH? And, you know, I'm sure your hematologist explained this to you.
Walk us through what your mindset was when you get a diagnosis of PNH, and how did your hematologist explain this to you?
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