Lactate dehydrogenase
Nutritional product - proteinsWikipedia
74
MENTIONS
38
EPISODES
32
PODCASTS
Search complete. 74 mentions across 38 episodes found for "Lactate dehydrogenase".
Nov 3, 2026
Amie BurbridgeHOST
there any blood tests that you would do to help indicate increased cell turnover within the body? Yeah, so
Ben LovellHOST
moving on to things like my general sort of haematological screen, your LDH and your BG microglobulin as well would be useful.
Amie BurbridgeHOST
Would I speak to heme at this point? Anemia?
Ben LovellHOST
So she's got one line down.
RebeccaHOST
These compounds weren't tested to see whether they were psychoactive or acted on those types of receptors.
RebeccaHOST
They found they didn't exhibit an anti-inflammatory activity based on an LDH inhibition assay.
RobHOST
That doesn't really tell you very much at all, does it? Which doesn't
RebeccaHOST
really tell you a lot.
Jin W. SungHOST
Hypoglycemia, functional.
Jin W. SungHOST
This is fasting glucose below 85, and you'll have another marker called LDH, or lactate dehydrogenase, and that will be below 140.
Jin W. SungHOST
That could be indicative of hypoglycemia.
Jin W. SungHOST
Symptoms are unrelated to any type of disease or medication and symptoms are resolved when you eat.
Jin W. SungHOST
Hypoglycemia, functional.
Jin W. SungHOST
This is fasting glucose below 85, and you'll have another marker called LDH, or lactate dehydrogenase, and that will be below 140.
Jin W. SungHOST
That could be indicative of hypoglycemia.
Jin W. SungHOST
Symptoms are unrelated to any type of disease or medication and symptoms are resolved when you eat.
Jin W. SungHOST
Hemoglobin A1C will sometimes will be below 5.
Jin W. SungHOST
Something called lactate dehydrogenase or LDH will be below 140.
Jin W. SungHOST
And then we also look at some of the minerals like chloride, potassium, and sodium to see if there's any adrenal dysfunction.
Jin W. SungHOST
You can also do other things like an adrenal panel.
Biree AndemariamGUEST
Your body's making more of these baby red blood cells to compensate.
Biree AndemariamGUEST
There are also some laboratory blood values that we check that look at some of those things that are released from the red blood cells when they hemolyze, and that's called LDH, lactate dehydrogenase, or LDH, as well as bilirubin.
Biree AndemariamGUEST
Bilirubin is the yellow substance that makes your eyes yellow when you have hemolysis.
Biree AndemariamGUEST
So those are the three most commonly that are sent.
Biree AndemariamGUEST
And they're sent sometimes together with the hemoglobin.
Biree AndemariamGUEST
So individuals can look back.
Biree AndemariamGUEST
You can look at your laboratory records and see what your LDH bilirubin, usually the indirect bilirubin, and your reticulocyte count are.
Golie GreenHOST
This is very, very helpful.
Joanie JacksonGUEST
And that's something we can measure in the blood.
Joanie JacksonGUEST
I measure it on every single one of my patients that are dealing with an oncological diagnosis and LDH.
Joanie JacksonGUEST
And because that tells me kind of how much lactase is being produced, where are we at as far as treatment, and I can use that sort of as another tool, another marker to gauge what we're doing therapy-wise.
Joanie JacksonGUEST
But with that, when LDH is going up, that correlates with something called HIF-1, and that's that hypoxic intrinsic factor.
Joanie JacksonGUEST
So HIF-1, again, low oxygen.
Joanie JacksonGUEST
So when we're using things like ozone, which is a supercharged, hyperoxygenated, it's going to disrupt all of that.
9 MINS LATER
Joanie JacksonGUEST
absolutely.
Joanie JacksonGUEST
And let's
Christopher BaligaGUEST
So how do you diagnose this? You're Aged less than 21 is primarily kids, and I think it was 5 to 12 was the age that was most impacted.
Christopher BaligaGUEST
They have persistent fever with two organ system involvements, so cardiac, respiratory, renal, hematologic, GI, dermatologic, or neurologic complications, elevated inflammatory markers, which are CRP, sed rate, ferritin, procal, IL-6, LDH, fibrinogen, D-dimer, elevated neutrophils, low lymphocytes, low albumin, and severe illness requiring hospitalization.
Christopher BaligaGUEST
You have to have some positive evidence of COVID within the last 60 days if you're doing a PCR or a history of COVID exposure or positive serology.
Christopher BaligaGUEST
I don't know how helpful that is because almost everyone is going to have immunity now against COVID.
KaleHOST
And if you are incredibly unlucky and your DLBCL decides to circulate, you could have a lymphocytosis, but that's probably as rare as hen's teeth.
NickHOST
The LDH, or lactate dehydrogenase, might be elevated, and spontaneous tumour lysis is possible with very bulky disease that is starting to break itself down.
NickHOST
Have a listen to episode 103 if you need a refresher on how we diagnose TLS.
NickHOST
It's a really good point, Cale, about circulating disease.
11 MINS LATER
Jed KitsonGUEST
Remember, the journal center has a dark zone where central blasts are proliferating and undergoing somatic hypermutation, and a light zone where they're selected based on their antigen affinity.
Jed KitsonGUEST
If a lymphoma has high expression of DZ-associated genes, as in DZ-sig positive, then this tells you that you've got a more aggressive lymphoma.
Jed KitsonGUEST
DZ-SIG is where you find our double-hit MYC and BCL-2 lymphomas, which tend to present with advanced disease, bone marrow involvement, and high LDH.
Jed KitsonGUEST
They have a predilection for the CNS, with high rates of involvement both at diagnosis and at relapse, and they have poor outcomes from standard immunochemotherapy.
Michael KarlfeldtGUEST
So I do the same.
Michael KarlfeldtGUEST
I also look at LDH, sed rate, C-reactive protein, and then also a lot of the other ones that are really important, like fibrinogen, ferritin, homocysteine level.
Michael KarlfeldtGUEST
And you want to obviously make sure that the blood sugar regulation is appropriate And then we can check for like VEGF and a lot of cancer drivers, IGF-1 that are important to look at.
Michael KarlfeldtGUEST
And also like TSH, for instance, a lot of people don't realize that it is a stimulating hormone in itself to stimulate growth.
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