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Experts InSight

Experts InSight

Challenges in DME: the Evolution of Fluid Management

May 28, 2026 · 31 min · 12 segments

With an abundance of therapeutic options for managing diabetic macular edema (DME), what patient characteristics inform your treatment decisions? Does the number of loading doses influence long-term…

With an abundance of therapeutic options for managing diabetic macular edema (DME), what patient characteristics inform your treatment decisions? Does the number of loading doses influence long-term macular fluid outcomes? How are you managing insurance-mandated step-therapy in your patients? In today's episode, host Dr. Jay Sridhar invites Drs. Durga Borkar and Carl Danzig to share how they've integrated new anti-VEGF therapies into clinical practice. For all episodes or to claim CME credit for selected episodes, visit www.aao.org/podcasts.

With an abundance of therapeutic options for managing diabetic macular edema (DME), what patient characteristics inform your treatment decisions? Does the number of loading doses influence long-term…

Speakers: Jay SridharHostDurga BorkarGuestCarl DanzigGuest

Spotify Apple Podcasts YouTube Amazon Music Website

Top entities: age related macular degeneration×27 Durga Borkar×14 Photon×7 Tyrosine kinase inhibitor×4 Yosemite National Park×8

Show signals: SuitabilitySafeBiasNot politicalAudience≈80k followers

Host & Guest Introductions0:40 – 1:25

Jay SridharHost

0:40

Welcome back to another episode of Experts in Sight.

Jay SridharHost

0:42

This is the official podcast of the American Academy of Ophthalmology.

Jay SridharHost

0:45

I'm your host for today's episode, Dr. Jay Schrieder.

Jay SridharHost

0:47

I'm a retinal surgeon practicing in Los Angeles, California.

Jay SridharHost

0:50

I'm very happy today to be joined by two colleagues to discuss the management of fluid and diabetic macular edema and how it's evolved and what we see today in twenty twenty-six.

Jay SridharHost

0:58

Uh, first in alphabetical order, I'm happy to be joined by Dr. Durga Borkar.

Jay SridharHost

1:01

Dr. Borkar is faculty at Duke University in Durham, North Carolina.

Jay SridharHost

1:05

Durga, thanks so much for joining the podcast.

Durga BorkarGuest

1:07

Thanks for having me, Jay.

Jay SridharHost

1:09

And I'm happy to be joined as well by Dr. Carl Danzig.

Jay SridharHost

1:12

Uh, Dr. Danzig is a retina specialist practicing with the Advanced Retina Instit-Institute in Naples, Florida.

Jay SridharHost

1:18

Uh, being a South Florida native, uh, Carl and I have a lot of overlap in our interests, not just geography.

Jay SridharHost

1:23

So Carl, welcome.

Jay SridharHost

1:24

Good to have you.

Carl DanzigGuest

1:25

Thanks for having me.

age related macular degenerationEntityDisease
98%27 mentions
Durga BorkarPerson
94%14 mentions
PhotonEntity
90%7 mentions
Tyrosine kinase inhibitorEntityPharmaceutical drug
85%4 mentions
Yosemite National ParkLandmarkNational park in California
81%8 mentions
anti vascular endothelial growth factor therapyEntity
77%7 mentions
FloridaAdministrative AreaUS state
73%2 mentions
OphthalmologyEntityBranch of medicine
69%1 mention
American Academy of OphthalmologyCompanyMedical association
65%4 mentions
NaplesCityCity in Florida
60%2 mentions
PodcastEntity
56%3 mentions
Duke UniversityCollege or UniversityPrivate university in Durham, North Carolina
52%2 mentions
macula of retinaEntity
48%1 mention
AppleCompanyTechnology company
44%1 mention
North CarolinaAdministrative AreaUS state
40%2 mentions
Hemoglobin A1CEntityChemical compound
35%3 mentions
CaliforniaAdministrative AreaUS state
31%1 mention
Los AngelesCityCity in California
27%3 mentions
Intraocular pressureEntity
23%3 mentions
South FloridaPlaceRegion in Florida
19%1 mention
DurhamCityCity in North Carolina
15%1 mention
Apple PodcastsSoftware Application
10%1 mention
BevacizumabEntityMedication
6%1 mention
Super Nintendo Entertainment SystemProductVideo game console
2%1 mention

HealthcareHealth
DiabetesHealth > Healthcare > Chronic Diseases
OphthalmologyHealth > Healthcare
Patient ManagementHealth > Healthcare
Treatment ProtocolsHealth > Healthcare > Patient Management
Drug EfficacyHealth > Healthcare > Pharmaceuticals
Diabetic Macular EdemaHealth > Healthcare > Ophthalmology
Patient OutcomesHealth > Healthcare > Clinical Trials > Drug Development
PharmaceuticalsHealth > Healthcare
Vision ImpairmentHealth > Healthcare > Chronic Diseases > Diabetes
Clinical TrialsHealth > Healthcare
Chronic DiseasesHealth > Healthcare
Anti-VEGF TherapyHealth > Healthcare > Ophthalmology > Diabetic Macular Edema
Real-World ApplicationsHealth > Healthcare > Patient Management > Treatment Protocols
Treatment StrategiesHealth > Healthcare > Pharmaceuticals > Drug Efficacy
Health
Drug DevelopmentHealth > Healthcare > Clinical Trials

Host & Guest Introductions0:40 – 1:25

Jay SridharHost

0:40

Welcome back to another episode of Experts in Sight.

Jay SridharHost

0:42

This is the official podcast of the American Academy of Ophthalmology.

Jay SridharHost

0:45

I'm your host for today's episode, Dr. Jay Schrieder.

Jay SridharHost

0:47

I'm a retinal surgeon practicing in Los Angeles, California.

Jay SridharHost

0:50

I'm very happy today to be joined by two colleagues to discuss the management of fluid and diabetic macular edema and how it's evolved and what we see today in twenty twenty-six.

Jay SridharHost

0:58

Uh, first in alphabetical order, I'm happy to be joined by Dr. Durga Borkar.

Jay SridharHost

1:01

Dr. Borkar is faculty at Duke University in Durham, North Carolina.

Jay SridharHost

1:05

Durga, thanks so much for joining the podcast.

Durga BorkarGuest

1:07

Thanks for having me, Jay.

Jay SridharHost

1:09

And I'm happy to be joined as well by Dr. Carl Danzig.

Jay SridharHost

1:12

Uh, Dr. Danzig is a retina specialist practicing with the Advanced Retina Instit-Institute in Naples, Florida.

Jay SridharHost

1:18

Uh, being a South Florida native, uh, Carl and I have a lot of overlap in our interests, not just geography.

Jay SridharHost

1:23

So Carl, welcome.

Jay SridharHost

1:24

Good to have you.

Carl DanzigGuest

1:25

Thanks for having me.

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