Apr 16, 2026 · 49 min · 15 segments
From building APIs in healthcare to building a “psychedelic system of record,” Niko Skievaski has always been ahead of the curve. In this episode, he shares how his entrepreneurial journey led him…
Niko SkievaskiGuestBrandon AnsleyHost
Yeah, well, so they're a class of drug that from a phenomenological perspective, like what you actually feel is, a loss of your identity in a lot of cases, which is absolutely terrifying.

You start to disassociate from who you think you are, the stories that you tell about yourself.

And there's different types of psychedelics, and there's different ways that people have defined them.

That's kind of how I think of them is these medicines, these drugs that will actually help you break down the stories that we have, the stories that create our reality.

And the texture of these altered states, depending on the type of medicine, is very different.

Some of them are very social where you might be talking a lot, but all of them help us break down what these stories are.

And when I think about it, you know, there are there are facts in life, things you can see with your eyes.

But most of the context that we live in is the stories about how we interpret those facts.

And I think psychedelics allow us to see those stories for what they are and actually question if they're true, question if they're 100% true or if they could be totally different.

And what it's physically doing in your brain is allowing different parts of your brain to start talking to each other that haven't been talking before.

And so it allows you, and especially in a creative line of work, like being an entrepreneur, it allows you to think of the world differently and get out of perspectives that may be holding you back.
And so to try to connect the dots here, the I think socially, the psychedelics, people might have heard of psychedelics by sort of their street names or, you know, or in movies or popular culture, but, you know, is it fair to say you know lsd acid mushrooms if you will unfortunately right in some case because whether they were misused or abused or what have you but but the the the science behind the molecules in those sort of recreational street drug names those are what we consider psychedelics right

And they actually, from a pharmacological standpoint, hit the same target in your brain, the serotonin 2A inhibitor.

Yeah, well, so they're a class of drug that from a phenomenological perspective, like what you actually feel is, a loss of your identity in a lot of cases, which is absolutely terrifying.

You start to disassociate from who you think you are, the stories that you tell about yourself.

And there's different types of psychedelics, and there's different ways that people have defined them.

That's kind of how I think of them is these medicines, these drugs that will actually help you break down the stories that we have, the stories that create our reality.

And the texture of these altered states, depending on the type of medicine, is very different.

Some of them are very social where you might be talking a lot, but all of them help us break down what these stories are.

And when I think about it, you know, there are there are facts in life, things you can see with your eyes.

But most of the context that we live in is the stories about how we interpret those facts.

And I think psychedelics allow us to see those stories for what they are and actually question if they're true, question if they're 100% true or if they could be totally different.

And what it's physically doing in your brain is allowing different parts of your brain to start talking to each other that haven't been talking before.

And so it allows you, and especially in a creative line of work, like being an entrepreneur, it allows you to think of the world differently and get out of perspectives that may be holding you back.
And so to try to connect the dots here, the I think socially, the psychedelics, people might have heard of psychedelics by sort of their street names or, you know, or in movies or popular culture, but, you know, is it fair to say you know lsd acid mushrooms if you will unfortunately right in some case because whether they were misused or abused or what have you but but the the the science behind the molecules in those sort of recreational street drug names those are what we consider psychedelics right

And they actually, from a pharmacological standpoint, hit the same target in your brain, the serotonin 2A inhibitor.
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