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5-MeO-DMT

5-MeO-DMT

Search complete. 198 mentions across 69 episodes found for "5-MeO-DMT".

Sep 11, 2026

Neal BrennanGUEST
13:39
Maybe it's up to 20 at this point, uh, 15, 20.
Neal BrennanGUEST
13:42
Then I did, uh, bufo, 5-MeO-DMT, the nuclear bomb of, of, uh, of psychedelics, and it, it was like it, it changed my brain chemistry.
Dan HarrisHOST
13:53
Which one? Ayahuasca, DMT, or the-
Neal BrennanGUEST
13:55
Uh, both of them

10 MINS LATER

Neal BrennanGUEST
24:22
Like, the fact that he, he ma- he's like, "I'm gonna make a movie in Aramaic and in a more obscure language," and they're still [laughs] gonna be great and big hits.
Neal BrennanGUEST
24:30
There, it, there's a lot of God stuff in, in Apocalypto, and it is, it really does feel that profound.
Neal BrennanGUEST
24:35
So in the midst, maybe around, uh, between ayahuasca 13 and 14, I did, um, 5-MeO-DMT, which is, uh, Bufo alvarius.
Neal BrennanGUEST
24:50
It's a, the f- toad secretion that they turn to a powder and you smoke it.
Amy CharlesworthGUEST
36:01
I had three medicines.
Amy CharlesworthGUEST
36:03
I had MDMA, psilocybin and 5-MeO-DMT and it saved my life.
Amy CharlesworthGUEST
36:09
And it wasn't going to be a one session thing that did that.
Amy CharlesworthGUEST
36:12
It was the completely, forgive my language here, but pulverizing, for lack of a better word, my brain, I needed that.
Wiz BuckleyGUEST
49:12
I mean, last week, Eli Lilly came in and bought a tie.
Wiz BuckleyGUEST
49:16
A company, a psychedelic company working on 5-MeO-DMT.
Wiz BuckleyGUEST
49:20
So Big Pharma...
Wiz BuckleyGUEST
49:21
It's starting to poke around this space like, wait a minute, we might be in trouble here.
Matt GutmanSOUNDBITE_SPEAKER
4:59
Um, all of them were great, I would say.
Matt GutmanSOUNDBITE_SPEAKER
5:05
Uh, I'll describe my experience with 5-MeO-DMT.
Matt GutmanSOUNDBITE_SPEAKER
5:10
Um, this is the secretions of a Sonoran desert toad.
Matt GutmanSOUNDBITE_SPEAKER
5:15
Um, it's, uh, basically a powder that you smoke.
Sue HitzmannHOST
34:54
It's like a spiritual bypass.
Sue HitzmannHOST
34:56
Just because you do 5-MeO-DMT, which is an amazing moment, people never come back the same.
Sue HitzmannHOST
35:03
But that's just the doorway into a different mind chatter.
Sue HitzmannHOST
35:07
You can't spiritually bypass things.
Cesar MarinGUEST
49:51
It's always this seesaw.
Cesar MarinGUEST
49:52
right and i think it's how the more people step in the middle of the seesaw because it can't be it cannot be hey wonderful eli lily now has this dmt spray that can help you with depression but it costs four thousand dollars yeah what are you talking about i can find a shaman that serves bufo 5meo dmt and have an experience the same experience for four hundred dollars What's the difference? That the other one's going to be in a clinic with some doctors, with some lab table, with some whatever.
Cesar MarinGUEST
50:29
Now, here's the thing.
Cesar MarinGUEST
50:30
If you're not comfortable with the shaman, with doing it in your house, with smoking out of a pipe that's got toad venom in it, and you have the $4,000 and that's going to help you with your depression, more power to you.
Cesar MarinGUEST
52:23
You're going to have someone who's not going to feel comfortable doing this in an underground manner, right? And they're going to go to the 5,000, 6,000, if they have that possibility.
Cesar MarinGUEST
52:36
Or the other thing is, it's going to be talked about more.
Cesar MarinGUEST
52:39
And someone's going to say, oh, wait a minute, DMT, what is, oh, wait, Eli Lilly and 5MEO DMT.
Cesar MarinGUEST
52:44
And it's in that, okay, that's Bufo.
Adam ButlerGUEST
12:00
And that is one of the things specific about DMT separate from all of the psychedelics.
Adam ButlerGUEST
12:04
Well, 5-MeO is also produced in our body.
Adam ButlerGUEST
12:07
But because it's natural to ourselves, it's metabolized very easily, quickly, without any hangover.
Adam ButlerGUEST
12:14
When you smoke the DMT crystals, it only lasts seven or eight minutes.
Raven LeeHOST
15:42
I'm really interested in this whole situation that you did.
Adam ButlerGUEST
15:46
So prior to that and not too far before that, I had done a really intense psychedelic retreat where I did a full dose of LSD, a full dose of MDMA.
Adam ButlerGUEST
15:55
I was ripping the 5-MeO DMT pen for hours, and I did a dose of shrooms.
Adam ButlerGUEST
16:00
And it was like in a 7-hour, 8-hour period.
Bret MaverickGUEST
56:28
Ibogaine.
Mary O'Neill PhillipsHOST
56:28
And the 5-MeO.
Bret MaverickGUEST
56:28
Yes.
Mary O'Neill PhillipsHOST
56:29
Yeah.
Sidney GordonGUEST
87:57
Um, and, like, the last two weeks it's been, like, amazing, right? So, but prior to that, you know, when, when I was really lost and I had some betrayal, I was not doing so well.
Sidney GordonGUEST
88:08
I was taking the betrayal out on people here, and then I ended up going down to, to Tijuana and doing Ibogaine and 5-MeO-DMT.
Sidney GordonGUEST
88:17
And I'll tell you right now, if you're on the fence with faith and you go and do what I did-
Mel ChanceyHOST
88:23
Mm-hmm
Rosalind WattsHOST
20:05
So episode one is me talking with sin.
Rosalind WattsHOST
20:09
from Asa, who was part of a 5-MeO-DMT clinical trial for depression and found that it led to extreme and unexpected anxiety and panic attacks that she's still having.
Rosalind WattsHOST
20:22
We also hear from Indira, from Asa, who had lifelong IBS and for whom psychedelic therapy was actually the solution was what finally helped this intractable and really, really difficult condition to resolve.
Rosalind WattsHOST
20:38
And she says now she doesn't have IBS.

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