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Lead: Adjunctive psychosocial interventions and opioid abstinence among patients receiving buprenorphine: A randomized clinical trial
Jul 7, 2026 · 8 min · 11 segments
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Adjunctive psychosocial interventions and opioid abstinence among patients receiving buprenorphine: A randomized clinical trial
*JAMA Network Open*
This randomized clinical trial of 340 adults with opioid use disorder (OUD) taking buprenorphine examined the comparative effectiveness of 2 psychosocial treatments—cognitive- behavioral therapy (CBT) and peer recovery support (PRS)—on opioid abstinence when used as adjunctive therapy to office-based buprenorphine treatment in adults with OUD. Researchers found that neither PRS, CBT, nor a combination of these psychosocial interventions yielded differential effects on opioid abstinence. These results suggest that adjunctive psychosocial interventions may not enhance buprenorphine treatment outcomes in the early stages of treatment.
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