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PETRI DISH PERSPECTIVES

PETRI DISH PERSPECTIVES

Episode 64: Conception Bio

Jul 16, 2026 · 23 min · 12 segments

Send us Fan Mail In this episode of *Petri Dish Perspectives*, we explore the story of **Conception Bio**, one of the most ambitious biotechnology…

Send us Fan Mail In this episode of *Petri Dish Perspectives*, we explore the story of **Conception Bio**, one of the most ambitious biotechnology companies working at the intersection of stem cell biology, reproductive medicine, and regenerative science. Their mission? To make eggs from ordinary cells through **in vitro gametogenesis (IVG),** a breakthrough that could fundamentally change how we think about infertility, fertility preservation, and human reproduction. We'll dive into the science behind IVG, the pioneering research that made the field possible, the founders' vision, and why investors believe reproductive biology could become one of biotech's next major frontiers. We'll also discuss the enormous technical hurdles, ethical questions, and potential applications for cancer survivors, age-related infertility, LGBTQ+ family building, and beyond. Because the next revolution in medicine may not be about curing disease, it may be about creating life's very first cell. 🎧 **Listen now, stay curious, and don’t forget to subscribe for new episodes every Thursday!** https://linktr.ee/maneadkhin #PetriDishPerspectives #ConceptionBio #Fertility #IVF #StemCells #RegenerativeMedicine #Biotech #ReproductiveBiology #InVitroGametogenesis #IVG #DrugDiscovery #Healthcare #LifeSciences #DevelopmentalBiology #PrecisionMedicine #WomenInScience #Biotechnology #SciencePodcast #FutureOfMedicine #BiotechPodcast Support the show © 2026 The Perspective Bureau LLC. All rights reserved.

Send us Fan Mail In this episode of *Petri Dish Perspectives*, we explore the story of **Conception Bio**, one of the most ambitious biotechnology…

Speakers: Manead KhinHost

Spotify Apple Podcasts YouTube Amazon Music Website

Top entities: in vitro fertilization×16 Company×2 Katsuhiko Hayashi×8 Sam Altman×3 Food and Drug Administration×3

Show signals: SuitabilitySafeAudience≈433 followers

The Egg Bottleneck0:18 – 1:45

M

Manead KhinHost

0:18

Alright, so if I asked you, what do you think is the most valuable cell in the human body? You might say a stem cell, you might say a brain cell, or maybe an immune cell that fights cancer.

M

Manead KhinHost

0:31

But what if the answer is an egg? Every human life begins with one.

M

Manead KhinHost

0:36

Yet, women are born with finite supply.

M

Manead KhinHost

0:40

And unlike with almost every other cell in the body, eggs cannot regenerate.

M

Manead KhinHost

0:45

So their quality drops with age, and fertility treatments are expensive, physically brutal, and still dependent on one thing that hasn't changed in decades, that depends on the fact that you need the eggs from a human body.

M

Manead KhinHost

0:59

That is the bottleneck.

M

Manead KhinHost

1:01

Not IVF, not embryo selection, not the tech in the lab, the egg itself.

M

Manead KhinHost

1:06

Conception Bible actually thinks that this assumption is worth challenging.

M

Manead KhinHost

1:10

Their goal isn't to make IVF better, it's to manufacture human eggs from ordinary cells entirely outside the body.

M

Manead KhinHost

1:20

If that sounds like a science fiction, that's because until very recently, it was.

M

Manead KhinHost

1:25

Today, we're going deep in one of the most audacious beds in modern biotech, a company trying to do something no one has ever done before, which is engineer the most fundamental building block of human life, an egg.

M

Manead KhinHost

1:39

Quick disclaimer, I give full credit to the original article, sign the references in the transcript, grab a coffee or tea, settle in, and let's jump right in.

in vitro fertilizationEntity
97%16 mentions
CompanyEntityOrganization type
91%2 mentions
Katsuhiko HayashiPersonJapanese geneticist
85%8 mentions
Sam AltmanPersonCEO of OpenAI
79%3 mentions
Food and Drug AdministrationGovernment OrganizationFederal agency
74%3 mentions
LinktreeWebsiteSite
68%1 mention
JapanCountryCountry in East Asia
62%2 mentions
LGBTQEntity
56%1 mention
CRISPREntity
50%2 mentions
Bedrock Fund Management, LLCCompanyCompany
44%2 mentions
Y CombinatorCompanyStartup accelerator company
38%1 mention
Induced pluripotent stem cellEntity
32%1 mention
Messenger RNAEntity
26%1 mention
Louise BrownPersonPhysician
21%1 mention
Kyoto UniversityCollege or UniversityNational university in Kyoto, Japan
15%1 mention
OpenAICompanyGenerative AI company
6%1 mention
SkypeSoftware ApplicationSoftware program
6%1 mention

Social IssuesSociety
Society
HealthcareHealth
Reproductive EthicsEthics > Bioethics
FertilityHealth > Healthcare > Reproductive Health
Stem Cell ResearchScience > Biology > Developmental Biology
Family PlanningSociety > Social Issues > Infertility
Developmental BiologyScience > Biology
BioethicsEthics
InfertilitySociety > Social Issues
Reproductive HealthHealth > Healthcare
Reproductive TechnologyTechnology > Biotechnology
IVF InnovationsTechnology > Biotechnology > Reproductive Technology
Health
Technology
BiotechnologyTechnology
Science
Ethics
In Vitro GametogenesisHealth > Healthcare > Reproductive Health > Fertility
Induced Pluripotent Stem CellsScience > Biology > Developmental Biology > Stem Cell Research
Egg ManufacturingTechnology > Biotechnology > Reproductive Technology > IVF Innovations
Access to Reproductive TechnologiesEthics > Bioethics > Reproductive Ethics
Ethical Implications of IVGEthics > Bioethics > Reproductive Ethics > Access to Reproductive Technologies
Reproductive AutonomySociety > Social Issues > Infertility > Family Planning
BiologyScience

The Egg Bottleneck0:18 – 1:45

M

Manead KhinHost

0:18

Alright, so if I asked you, what do you think is the most valuable cell in the human body? You might say a stem cell, you might say a brain cell, or maybe an immune cell that fights cancer.

M

Manead KhinHost

0:31

But what if the answer is an egg? Every human life begins with one.

M

Manead KhinHost

0:36

Yet, women are born with finite supply.

M

Manead KhinHost

0:40

And unlike with almost every other cell in the body, eggs cannot regenerate.

M

Manead KhinHost

0:45

So their quality drops with age, and fertility treatments are expensive, physically brutal, and still dependent on one thing that hasn't changed in decades, that depends on the fact that you need the eggs from a human body.

M

Manead KhinHost

0:59

That is the bottleneck.

M

Manead KhinHost

1:01

Not IVF, not embryo selection, not the tech in the lab, the egg itself.

M

Manead KhinHost

1:06

Conception Bible actually thinks that this assumption is worth challenging.

M

Manead KhinHost

1:10

Their goal isn't to make IVF better, it's to manufacture human eggs from ordinary cells entirely outside the body.

M

Manead KhinHost

1:20

If that sounds like a science fiction, that's because until very recently, it was.

M

Manead KhinHost

1:25

Today, we're going deep in one of the most audacious beds in modern biotech, a company trying to do something no one has ever done before, which is engineer the most fundamental building block of human life, an egg.

M

Manead KhinHost

1:39

Quick disclaimer, I give full credit to the original article, sign the references in the transcript, grab a coffee or tea, settle in, and let's jump right in.

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