Aug 28, 2026 · 12 min · 8 segments
In this episode of Overnight Success, I sit down with Kobie Fuller, General Partner at Upfront Ventures—the most iconic VC firm in Los Angeles and a cornerstone of the city’s startup ecosystem. We…
Kobie FullerGuestChris JoannouHost
We're wired to community build and do it in a way where it's not all about like, oh, how can we just make a billion dollars? It is the most exciting period of time in my investing career because the things that we're seeing, it feels like science fiction.

All those things you read about in books growing up as a kid from like, robotics, self-driving cars, AI that can act as a personal companion like her.

We're investors in all sorts of stuff I can't even actually still understand stealth.

And then on the enterprise software side of things, being able to leverage the technology to solve problems in ways that never before were even possible.

So a total disruption in terms of how you even think about enterprise software.


People historically, at least the first couple years or year when you started seeing ChatGPT hit the market, there was this notion around like, oh, that's just a wrapper.

Like, it's built on top of some other underlying technology with Amazon S3 or whatever sort of underlying sort of database architecture.

And so the things that for me are really exciting is that you can leverage these underlying LLMs that have a level of reasoning and knowledge that if you were to pair with some proprietary knowledge, curated knowledge, An example of which, I'm an investor in a company called 1UP that's focusing on sales knowledge to help automate a wedge problem they're solving is the completion of RFPs.

So during a process when you're trying to go through a sales motion, usually RFPs takes two weeks to complete out.

These things will take like... seconds because it taps into a proprietary knowledge base that you would have within your organization around your specific product.

And then there's a transformation of that leveraging an LLM to then complete an RFP.

These are ways in which this knowledge layer on top of standard LLMs can transform industries in a manner we've never seen before possible.

So I'm looking to invest in as many permutations of knowledge systems as possible because for me, it's the next wave of of enterprise software and applications that are leveraging AI.

We're wired to community build and do it in a way where it's not all about like, oh, how can we just make a billion dollars? It is the most exciting period of time in my investing career because the things that we're seeing, it feels like science fiction.

All those things you read about in books growing up as a kid from like, robotics, self-driving cars, AI that can act as a personal companion like her.

We're investors in all sorts of stuff I can't even actually still understand stealth.

And then on the enterprise software side of things, being able to leverage the technology to solve problems in ways that never before were even possible.

So a total disruption in terms of how you even think about enterprise software.


People historically, at least the first couple years or year when you started seeing ChatGPT hit the market, there was this notion around like, oh, that's just a wrapper.

Like, it's built on top of some other underlying technology with Amazon S3 or whatever sort of underlying sort of database architecture.

And so the things that for me are really exciting is that you can leverage these underlying LLMs that have a level of reasoning and knowledge that if you were to pair with some proprietary knowledge, curated knowledge, An example of which, I'm an investor in a company called 1UP that's focusing on sales knowledge to help automate a wedge problem they're solving is the completion of RFPs.

So during a process when you're trying to go through a sales motion, usually RFPs takes two weeks to complete out.

These things will take like... seconds because it taps into a proprietary knowledge base that you would have within your organization around your specific product.

And then there's a transformation of that leveraging an LLM to then complete an RFP.

These are ways in which this knowledge layer on top of standard LLMs can transform industries in a manner we've never seen before possible.

So I'm looking to invest in as many permutations of knowledge systems as possible because for me, it's the next wave of of enterprise software and applications that are leveraging AI.
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