Oct 5, 2026 · 24 min · 11 segments
Picture a field of wheat blowing in the wind. It looks serene, and the wheat looks healthy - especially because the wheat farmer has sprayed a triazole fungicide to stop mold from damaging the crop…
Alex ClohertyHost
Merel SijbrandaHost
It looks serene and the wheat looks healthy, especially because the wheat farmer has sprayed a fungicide to stop mold from damaging the crop.
In the hospital, a patient with reduced immune functioning, maybe because he or she has leukemia or HIV, in any case, an illness that reduces the ability of the immune system to combat infections.
The doctors reach for a fungicide, and it's the same drug class that's used on the wheat fields only a few kilometers away, but then it doesn't work for the patient.
This is exactly the future that we're trying to avoid with antifungals, where the overuse of antifungal agents in one area of life can mean that the drug no longer works when we need it to in another area of life.
It's a similar concept to antibiotic resistance, but actually maybe even more challenging.
Today, we're diving into what makes fungi different, what we need to consider when using antifungals for different purposes, and the impact that this could have on our lives in the future.
It looks serene and the wheat looks healthy, especially because the wheat farmer has sprayed a fungicide to stop mold from damaging the crop.
In the hospital, a patient with reduced immune functioning, maybe because he or she has leukemia or HIV, in any case, an illness that reduces the ability of the immune system to combat infections.
The doctors reach for a fungicide, and it's the same drug class that's used on the wheat fields only a few kilometers away, but then it doesn't work for the patient.
This is exactly the future that we're trying to avoid with antifungals, where the overuse of antifungal agents in one area of life can mean that the drug no longer works when we need it to in another area of life.
It's a similar concept to antibiotic resistance, but actually maybe even more challenging.
Today, we're diving into what makes fungi different, what we need to consider when using antifungals for different purposes, and the impact that this could have on our lives in the future.
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