Alzheimer’s Breakthrough with Dr. Josh Helman, MD
Nov 5, 2026 · 57 min · 12 segments
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John GoldmanGuest
Josh HelmanHost
And when you do it with the cardiometabolic cart, it analyzes how much of your energy is coming from fat and then how much of your energy burn is coming from fat.

And then if you pair it with a lactate threshold testing, we can see your lactose lactate numbers on a curve as your heart rate goes up.

And then we can come up with not only your VO2 max number, but also your lactate threshold.

And so that VO2 max number, you do it, you go into, we often refer people to exercise science departments at universities.

It's a treadmill test where you progressively move more quickly over time, starting with a brisk walk and then moving up to pretty much as fast as you can go for as long as you can go and seeing what your max

And then we use that information because VO2 max is a test of your cardiorespiratory fitness.

Your cardiorespiratory fitness is perhaps the most valuable leading indicator for your longevity of any indicator that we have.

You reduce your chance for all-cause mortality significantly from moving from the poor group to the good group.

I've seen some numbers thrown around, but generally speaking, the benefit that you get from doing that is far greater than you get from even quitting smoking.

And when you do it with the cardiometabolic cart, it analyzes how much of your energy is coming from fat and then how much of your energy burn is coming from fat.

And then if you pair it with a lactate threshold testing, we can see your lactose lactate numbers on a curve as your heart rate goes up.

And then we can come up with not only your VO2 max number, but also your lactate threshold.

And so that VO2 max number, you do it, you go into, we often refer people to exercise science departments at universities.

It's a treadmill test where you progressively move more quickly over time, starting with a brisk walk and then moving up to pretty much as fast as you can go for as long as you can go and seeing what your max

And then we use that information because VO2 max is a test of your cardiorespiratory fitness.

Your cardiorespiratory fitness is perhaps the most valuable leading indicator for your longevity of any indicator that we have.

You reduce your chance for all-cause mortality significantly from moving from the poor group to the good group.

I've seen some numbers thrown around, but generally speaking, the benefit that you get from doing that is far greater than you get from even quitting smoking.
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