The Lancet Neurology in conversation with
Jun 17, 2026 · 16 min · 9 segments
In this episode of In Conversation With, Morgane Boillot, Senior Editor at The Lancet Neurology, speaks with connective tissue disorders — including Marfan syndrome — and human genetics expert Hal…
Hal DietzGuest
Morgane BoillotHost
To an extent, they are expressed in different tissues, but perhaps the bigger factor is that fibrillin-2 is largely expressed during early embryonic and early childhood development, whereas fibrillin-1 expression emerges later in childhood and into adulthood.

So different developmental stages are relevant to the expression of these proteins.

To an extent, they are expressed in different tissues, but perhaps the bigger factor is that fibrillin-2 is largely expressed during early embryonic and early childhood development, whereas fibrillin-1 expression emerges later in childhood and into adulthood.

So different developmental stages are relevant to the expression of these proteins.
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