Sital KhistryaGuest
Jasmin DhillonHost
Amanda LimHost
Now, do the ramifications of PMOS or honestly metabolic dysfunction generally, do those vary by ethnicity at all?


So typically Caucasian or Eastern European people And that meant that the diagnostic criteria, which is the irregular periods, excess hair or acne, and then potential cysts on a scan, were derived from that cohort.

They actually present, as you've already highlighted here, they present with insulin resistance at a much lower BMI.

This is the classic slim profile lady, potentially, who has underlying insulin resistance or is able to reverse it, as you've said, but actually they're more at a risk of it coming back and that insulin resistance creeping back in, causing that ovarian dysfunction and then the knock-on, knock-on effect.

The East Asian women's are also another subgroup who get ignored because they're so slim.

And they also don't have the genes that promote that excessive hair change that you more readily see in South Asian women.

And then you've got Hispanic groups and black groups which show up differently as well.

So Hispanic women carry a larger insulin resistance load anyway, and their hirsutism is worse.

But the black community have a higher risk of blood pressure possibly being their only symptom.

Oh, really? So theirs is the cardiovascular disease element that can cause the problems earlier on.

So at a younger age, if you're seeing someone with high blood pressure, we should be doing a full workup looking at those metabolic risk factors underneath.

So what you're saying is non-Caucasian women need to be potentially more vigilant about monitoring symptoms that on paper don't look like PMOS.

And in Asian skin, South Asian skin, and in black communities, I personally think a condition called acanthosis nigrican, which is the leathery.

Now, do the ramifications of PMOS or honestly metabolic dysfunction generally, do those vary by ethnicity at all?


So typically Caucasian or Eastern European people And that meant that the diagnostic criteria, which is the irregular periods, excess hair or acne, and then potential cysts on a scan, were derived from that cohort.

They actually present, as you've already highlighted here, they present with insulin resistance at a much lower BMI.

This is the classic slim profile lady, potentially, who has underlying insulin resistance or is able to reverse it, as you've said, but actually they're more at a risk of it coming back and that insulin resistance creeping back in, causing that ovarian dysfunction and then the knock-on, knock-on effect.

The East Asian women's are also another subgroup who get ignored because they're so slim.

And they also don't have the genes that promote that excessive hair change that you more readily see in South Asian women.

And then you've got Hispanic groups and black groups which show up differently as well.

So Hispanic women carry a larger insulin resistance load anyway, and their hirsutism is worse.

But the black community have a higher risk of blood pressure possibly being their only symptom.

Oh, really? So theirs is the cardiovascular disease element that can cause the problems earlier on.

So at a younger age, if you're seeing someone with high blood pressure, we should be doing a full workup looking at those metabolic risk factors underneath.

So what you're saying is non-Caucasian women need to be potentially more vigilant about monitoring symptoms that on paper don't look like PMOS.

And in Asian skin, South Asian skin, and in black communities, I personally think a condition called acanthosis nigrican, which is the leathery.
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