Ramin NilforooshanGuestFinally, the sense I'm getting from you is that there is a paradigm shift that is either taking place or is about to take place where perhaps more and more people will get tested and find out that they're at risk.
Today, in the absence of licensed treatments, because a lot of these are being researched but are not available, what things do you recommend people do in your practice when you're seeing somebody who is either in the early stages of dementia or at very high risk? What do you recommend that they do to try to reduce their risk or at least delay the onset?

I usually start saying that anything that is bad for heart is bad for brain.

There are a few publications, the Lancet publication about prevention, the way that we look at the risk factors.

And the controlling of blood pressure, it means your blood pressure around 135%.

We insist that bring the blood pressure down, make sure that bring your cholesterol down.

Sleep is really important because during the sleep time, the amyloid gets cleared from brain.

So I think if people don't get a good night's sleep and if it's become chronic, we ask them to go and see their clinician, start using sleep hygiene.

So we advise people to have regular exercise, go for a walk two or three times a week, even if it's for 20 minutes.

The other thing is about the hearing, the vision, the social isolations, all those things affect the way that the brain works.

So yes, we don't have a treatment for Alzheimer's, but there are things you could do to slow down progression.
Finally, the sense I'm getting from you is that there is a paradigm shift that is either taking place or is about to take place where perhaps more and more people will get tested and find out that they're at risk.
Today, in the absence of licensed treatments, because a lot of these are being researched but are not available, what things do you recommend people do in your practice when you're seeing somebody who is either in the early stages of dementia or at very high risk? What do you recommend that they do to try to reduce their risk or at least delay the onset?

I usually start saying that anything that is bad for heart is bad for brain.

There are a few publications, the Lancet publication about prevention, the way that we look at the risk factors.

And the controlling of blood pressure, it means your blood pressure around 135%.

We insist that bring the blood pressure down, make sure that bring your cholesterol down.

Sleep is really important because during the sleep time, the amyloid gets cleared from brain.

So I think if people don't get a good night's sleep and if it's become chronic, we ask them to go and see their clinician, start using sleep hygiene.

So we advise people to have regular exercise, go for a walk two or three times a week, even if it's for 20 minutes.

The other thing is about the hearing, the vision, the social isolations, all those things affect the way that the brain works.

So yes, we don't have a treatment for Alzheimer's, but there are things you could do to slow down progression.
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