Sep 29, 2026 · 45 min · 17 segments
Weight-loss drugs are everywhere in the headlines. But what might they mean for our health beyond the number on the scales? This week, Professor Afif EL-Khuffash and Dr Anne Doherty explore GLP-1…
Anne DohertyHost
Afif El-KhuffashHost
And I actually, I found when I started researching this topic because, you know, I actually had to get into GLP-1 agonists because...
And a lot of mums are breastfeeding that I deal with and they're asking me about whether they can breastfeed while they're taking it or not.
But it got me thinking about the actual peptide and it got me thinking about how it works.
So, you know, the story began with the observation that If you eat glucose, if you consume it enterally through your mouth and it hits your stomach, your insulin surge is much higher when you compare it to actually getting an injection of the same amount directly into your veins.
And the reason for that is when it goes through your gut, it stimulates a glucone like peptide, GLP.
Yes, there will be a slight passive aggressive tone for the entirety of the podcast.
And it is this hormone that actually stimulates or makes the pancreas more enthusiastic at releasing insulin.
And I actually, I found when I started researching this topic because, you know, I actually had to get into GLP-1 agonists because...
And a lot of mums are breastfeeding that I deal with and they're asking me about whether they can breastfeed while they're taking it or not.
But it got me thinking about the actual peptide and it got me thinking about how it works.
So, you know, the story began with the observation that If you eat glucose, if you consume it enterally through your mouth and it hits your stomach, your insulin surge is much higher when you compare it to actually getting an injection of the same amount directly into your veins.
And the reason for that is when it goes through your gut, it stimulates a glucone like peptide, GLP.
Yes, there will be a slight passive aggressive tone for the entirety of the podcast.
And it is this hormone that actually stimulates or makes the pancreas more enthusiastic at releasing insulin.
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