Latif NasserHost
Lulu MillerHostNow isn't that re- re- remarkably dumb? [laughs]

According to psychologist Linda Bartoszek, this whole ranked list is ridiculous.
Have you ever heard anybody say that saccharin is 100 times as sweet as sugar?
Have you ever tasted saccharin and sugar at the same time?
Well, I assure you, you will not think-
...
the saccharin is 100 times as sweet as sugar, for God's sake.
Well, uh, the, these sweeteners, they do have some off flavors.
Uh-

Eric says that the problem with coming up with a perfect sweetener is that there's only one sweetness receptor, but on the other hand-
Humans have, I don't know, 20 or 30 different bitter taste receptors

so it's like a minefield that you have to kind of tiptoe through to get to the promised land of the sweet receptor.
Yes.
Yes.

So it's really hard to develop a compound that triggers the sweet receptor but doesn't trigger any of the bitter receptors as well, which is why you get those off tastes from so many sweeteners.

But the food chemists, when they're ranking sweeteners, they are just looking at one very specific thing.
And that's a, a value that we refer to as potency.

They just want the thing you can use the smallest amount of to turn on that sweetness receptor.
Now isn't that re- re- remarkably dumb? [laughs]

According to psychologist Linda Bartoszek, this whole ranked list is ridiculous.
Have you ever heard anybody say that saccharin is 100 times as sweet as sugar?
Have you ever tasted saccharin and sugar at the same time?
Well, I assure you, you will not think-
...
the saccharin is 100 times as sweet as sugar, for God's sake.
Well, uh, the, these sweeteners, they do have some off flavors.
Uh-

Eric says that the problem with coming up with a perfect sweetener is that there's only one sweetness receptor, but on the other hand-
Humans have, I don't know, 20 or 30 different bitter taste receptors

so it's like a minefield that you have to kind of tiptoe through to get to the promised land of the sweet receptor.
Yes.
Yes.

So it's really hard to develop a compound that triggers the sweet receptor but doesn't trigger any of the bitter receptors as well, which is why you get those off tastes from so many sweeteners.

But the food chemists, when they're ranking sweeteners, they are just looking at one very specific thing.
And that's a, a value that we refer to as potency.

They just want the thing you can use the smallest amount of to turn on that sweetness receptor.
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