The Missing Link Between Hormones, Insulin Resistance & Heart Health | Dr. Sirisha Vadali EP355

Send us Fan Mail For years, women have been told that weight gain, irregular cycles, insulin resistance, elevated cholesterol, fatigue, and hormone imbalances are separate problems requiring separate solutions. But what if they're all connected? In this episode, Cody sits down with **Dr. Sirisha Vadali**, board-certified cardiologist, advanced lipidologist, and Program Director of HonorHealth's Cardiometabolic Program, to explore the growing understanding of women's metabolic health and why experts are rethinking the way we approach conditions like PCOS. Dr. Vadali explains why many experts now support the term **PMOS (Polyendocrine Metabolic Ovarian Syndrome)**, recognizing that this condition affects far more than the ovaries. Together, they discuss how hormones, insulin resistance, inflammation, metabolism, and cardiovascular health are deeply interconnected—and why understanding that bigger picture can completely change a woman's approach to her health. Whether you've struggled with weight loss, elevated cholesterol, insulin resistance, irregular cycles, or simply feel like your symptoms haven't been taken seriously, this conversation offers both validation and practical hope. In This Episode You'll Learn: - Why many experts are advocating for the shift from PCOS to PMOS - The surprising relationship between hormones, insulin resistance, and metabolism - Why cardiovascular health should be part of every woman's hormone conversation - Early signs of insulin resistance that often go unnoticed - Why women are frequently dismissed or misdiagnosed - How inflammation impacts hormones and long-term health - What cholesterol really tells us about metabolic health - Lifestyle habits that have the greatest impact on insulin sensitivity - Why quick fixes rarely create lasting results - Practical ways to reduce future cardiometabolic risk Key Takeaway Women's health isn't just about hormones. It's about understanding how hormones, metabolism, inflammation, insulin, and cardiovascular health all work together. When we stop treating symptoms in isolation and begin supporting the whole system, we create a much stronger foundation for long-term health. About Our Guest Dr. Sirisha Vadali is a board-certified cardiologist, advanced lipidologist, and Program Director of Honor Health's Cardiometabolic Program. Having cared for more than **120,000 patients**, she is passionate about prevention and helping women better understand the connection between metabolic health, hormones, cardiovascular disease, and longevity. Connect with Dr. Sirisha Vadali If you'd like to learn more from Dr. Vadali or connect with her work, you can find her here: 🌐 **Website:** www.sirishavadali.com ❤️ **HonorHealth Physician Profile:** HonorHealth Women's Cardiovascular Disease & Cardiometabolic Program 📸 **Instagram:** @vadalimd 💼 **LinkedIn:** Dr. Sirisha Vadali on LinkedIn Whether you're looking to learn more about women's heart health, cardiometabolic wellness, prevention, or the latest research in women's healthcare, Dr. Vadali shares valuable educational content and resources to help women better understand and advocate for their health. **If you enjoyed this episode...** Please subscribe, leave a review, and share this episode with a woman who deserves to understand what's really happening beneath the surface of her symptoms. Because when women understand their bodies, they make empowered decisions for their health. 💗 Did you learn something new today? Be sure to subscribe to this podcast and share this episode with all the girls you love. We would appreciate it if you'd also leave us a rating and review on iTunes. Want to join our Mixhers Girl community and keep this conversation going? We'd love to hear your thoughts, feelings and experiences! Join us HERE! Join Mixhers email list and be the first to have access to new products and be the girl in the know! Follow Cody Instagram: @codyjeansanders