Gastroenterology Learning Network
Aug 19, 2026 · 31 min · 9 segments
07.14.26-GLN-GutCheckHornblom_v1 by Gastroenterology Learning Network
Hans TornblomGuest
Brian LaceyHost
Your first question is a simple one, but very important, or perhaps not simple, but very important.
The DGBIs are a group of chronic gastrointestinal disorders in which symptoms arise from abnormal communication between the gastrointestinal tract and the brain, rather from structural abnormalities, I mean, comparing with ulcer disease or tumors, or readily identified by chemical markers otherwise.
The DVIs were previously known as functional gastrointestinal disorders, but the name was changed some 10 years ago to better reflect current scientific understanding that these conditions involve measurable disturbances in gut brain signaling, where people like you and I do research to find out what is it that are drivers for this abnormal gut brain signaling.
And when we think about the prevalence of DGBIs worldwide, how prevalent are they, and how prevalent are the gastro-denal disorders?
They are very common, and this has been extensively studied and described in the adult population during the recent years by the outcome of the Rome Foundation global epidemiology study that was performed in 26 countries worldwide by using internet service.
And overall the prevalence for having at least one DGBI fulfilling criteria for that and not having signs of any other organic disease explaining it was 40% among adults.
And the prevalence specifically of the gastrointestinal disorders was a bit more than 10%, 10.6%, with functional dyspepsia being the most common.
So Hans, you mentioned the Rome Committee, and the Rome Committee includes experts from around the world to help develop these criteria.
Well, according to the Rome 5 classification, categorize these disorders into functional dyspepsia, which we subcategorize into postprandial distress syndrome and epigastric pain syndrome.
chronic nausea and vomiting disorders, which are subcategorized into chronic nausea and vomiting syndrome, cyclic vomiting syndrome, and cannabinoid hyperemesis syndrome.
And we have the excessive belching disorders that are subcategorized into excessive gastric and supragastric belching.
And then we have a new category, when you belch too little, inability to belch syndrome, and finally rumination syndrome.
So we have one new category defined in the Rome 5 criteria compared to the Rome 4 criteria.
Your first question is a simple one, but very important, or perhaps not simple, but very important.
The DGBIs are a group of chronic gastrointestinal disorders in which symptoms arise from abnormal communication between the gastrointestinal tract and the brain, rather from structural abnormalities, I mean, comparing with ulcer disease or tumors, or readily identified by chemical markers otherwise.
The DVIs were previously known as functional gastrointestinal disorders, but the name was changed some 10 years ago to better reflect current scientific understanding that these conditions involve measurable disturbances in gut brain signaling, where people like you and I do research to find out what is it that are drivers for this abnormal gut brain signaling.
And when we think about the prevalence of DGBIs worldwide, how prevalent are they, and how prevalent are the gastro-denal disorders?
They are very common, and this has been extensively studied and described in the adult population during the recent years by the outcome of the Rome Foundation global epidemiology study that was performed in 26 countries worldwide by using internet service.
And overall the prevalence for having at least one DGBI fulfilling criteria for that and not having signs of any other organic disease explaining it was 40% among adults.
And the prevalence specifically of the gastrointestinal disorders was a bit more than 10%, 10.6%, with functional dyspepsia being the most common.
So Hans, you mentioned the Rome Committee, and the Rome Committee includes experts from around the world to help develop these criteria.
Well, according to the Rome 5 classification, categorize these disorders into functional dyspepsia, which we subcategorize into postprandial distress syndrome and epigastric pain syndrome.
chronic nausea and vomiting disorders, which are subcategorized into chronic nausea and vomiting syndrome, cyclic vomiting syndrome, and cannabinoid hyperemesis syndrome.
And we have the excessive belching disorders that are subcategorized into excessive gastric and supragastric belching.
And then we have a new category, when you belch too little, inability to belch syndrome, and finally rumination syndrome.
So we have one new category defined in the Rome 5 criteria compared to the Rome 4 criteria.
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