Sep 16, 2026 · 17 min · 8 segments
A "normal" cholesterol result can still hide real heart risk. Dr. Raina Patel explains ApoB, Lp(a), the new 2026 guidelines, how GLP-1s and weight loss change your lipids, the latest medications, and…
Raina PatelHost
Welcome back everyone to episode 23, where we will be discussing cholesterol guidelines that have changed this year in 2026.

So many of you probably have gone to your doctor, maybe your primary care physician, and gotten your annual blood work.

It is true that a high LDL level does put you at a higher risk of a heart attack or a stroke later on in life.

And previously we were looking at something called ASCVD risk score, and we would use this score and calculate it.

And based on your numbers, if needed, we would start you on a medication called a statin, which is a cholesterol lowering medication.

But now there are new markers that we're looking at, specifically lipoprotein A and apolipoprotein B.

And so these two markers were basically started in the 2026 cholesterol guidelines.

And I just want to touch upon them and kind of explain the importance of these specific markers.

Welcome back everyone to episode 23, where we will be discussing cholesterol guidelines that have changed this year in 2026.

So many of you probably have gone to your doctor, maybe your primary care physician, and gotten your annual blood work.

It is true that a high LDL level does put you at a higher risk of a heart attack or a stroke later on in life.

And previously we were looking at something called ASCVD risk score, and we would use this score and calculate it.

And based on your numbers, if needed, we would start you on a medication called a statin, which is a cholesterol lowering medication.

But now there are new markers that we're looking at, specifically lipoprotein A and apolipoprotein B.

And so these two markers were basically started in the 2026 cholesterol guidelines.

And I just want to touch upon them and kind of explain the importance of these specific markers.
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