
Bryan Pellegrino
CEO of LayerZero Labs
5
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Oct 16, 2026
Why the Top 2 VCs in Silicon Valley Are Betting on This Company | EO
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Bryan PellegrinoGUEST
[gentle music] I woke up one morning, April 15th, and I sat down at my computer, and there's a big seal of the Department of Justice, the DOJ, on the website.

Bryan PellegrinoGUEST
And what had happened was overnight they had banned all online poker within the United States.

Bryan PellegrinoGUEST
All of the payment processors are down, so you can no longer move money between or do anything, and it was just like overnight, like [snaps fingers] that, the industry was just gone.

Bryan PellegrinoGUEST
And I think those were the first times where you said, "Okay." You saw the reach of, of sort of policy and government sort of impacting you in your real life.
22 MINS LATER
Crypto Is Rebuilding The Financial System — And Opportunities Abound
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Avi FelmanHOST
Like, are there areas to improve? Or is it like we're on the blockchain where we're focused on our settlement product now?

Bryan PellegrinoGUEST
Ethereum transactions can take one second to complete, but you're taking some finality risk.
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Uneasy Money: Why Peter Steinberger and Non-Crypto People Hate the Crypto Mob
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Bryan PellegrinoGUEST
So I think there's, there's two sides why institutions are actually like care.

Bryan PellegrinoGUEST
One, why do institutions care? Institutions only care for one of two reasons.

Bryan PellegrinoGUEST
One is like a fear of being disrupted and wanting to be in front of it, right? Which is like a, a very like real thing for a bunch of them, is just like wanting...

Bryan PellegrinoGUEST
Like if everything's going to get disrupted, how can we be best positioned to actually capture like more of what that...
How Zero Blockchain Cracked 2M TPS Without Sacrificing Decentralization
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Laura ShinHOST
But talk a little bit about how you managed to resolve all those issues without compromising on something like decentralization.

Bryan PellegrinoGUEST
So again, core problem with any system, the main primary problem is this cost of replication, right? You run into two things, having every node download all of the transactions and all the data and needing to reproduce the compute across all of things.

Bryan PellegrinoGUEST
So the four breakthroughs that we solved along the way, the first was QMDB, which is actually a paper we published a year ago.

Bryan PellegrinoGUEST
It's now being rolled out like through Commonware and to Tempo and some of other chains that are launching now.

Bryan PellegrinoGUEST
It is 100x more performant than state-of-the-art for database structure for verifiable database.
9 MINS LATER
The Experts Weigh in on Intel, Big Family: The Ultimate Status Symbol | Wade Foster, Dan Wang, Nicolas Sharp, Shan Aggarwal, Vikas Enti, Bryan Pellegrino, Logan Kilpatrick, Rylan Hamilton
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181:46speaker_3UNKNOWN
but are less familiar.

Bryan PellegrinoGUEST
Yep, DAO is sort of, uh, fascinating, uh, idiosyncrasy within crypto itself, right? So, uh, DAO is Decentralized Autonomous Organization.

Bryan PellegrinoGUEST
We built this protocol, we launched it, and then we basically said, "Hey, governance is going to be left up to all the people who hold the token," right? So there's a bunch of people who hold the token, they have the ability to stake and, and actively vote on all kinds of things; how things get priced, how the dollars that the protocol owns or the protocol had accrued about $95 million worth of, worth of assets itself internally, like all kinds of things within it.

Bryan PellegrinoGUEST
Uh, and it was just running, and naturally as you can imagine, something that gets run by, you know, 50,000 people as opposed to, uh, a small group of very agile fast-moving, uh, entrepreneurs runs very differently, right? And so what this meant is a, a lot of things are slower than you would like them to.

Bryan PellegrinoGUEST
Innovation is sort of like slow in that side, so I mean, it was very dominant from a bridge perspective, that's what Stargate does is move assets around.
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184:43speaker_3UNKNOWN
Um, what i- what i- what, uh, what should we be looking out for in the back half of this year? I mean, uh, uh, four months I guess at this point, but in, in terms of, uh, uh, assets coming, coming on chain and tokenization broadly?
