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This EndoLife

What Does the Latest Research Tell Us About Endo Belly and the Microbiome of People With Endo?

Jul 5, 2026 · 11 min · 9 segments

As I am still recovering from covid, today’s episode is a short bite sized episode looking at what the recent research is telling us about the endo belly and the gut microbiome of people with endo…

As I am still recovering from covid, today’s episode is a short bite sized episode looking at what the recent research is telling us about the endo belly and the gut microbiome of people with endo. ***References*** 1\) https://pmc.ncbi.nlm.nih.gov/articles/PMC10316551/ 2\) https://pubmed.ncbi.nlm.nih.gov/28303579/ 3\) Endometriosis and irritable bowel syndrome: A systematic review and meta-analyses - PMC 4\) https://pubmed.ncbi.nlm.nih.gov/32949284/, https://pubmed.ncbi.nlm.nih.gov/32004880/, https://pmc.ncbi.nlm.nih.gov/articles/PMC10316551/ 5\) https://pubmed.ncbi.nlm.nih.gov/18715239/ 6\) https://pmc.ncbi.nlm.nih.gov/articles/PMC12942269/ 7) https://www.mdpi.com/2076-2607/11/8/2089 8\) https://www.mdpi.com/2077-0383/12/22/7176#B44-jcm-12-07176 ***Podcast links*** *Beta-glucuronidase:* https://www.theendobellycoach.com/podcast/sibo-gut-dysbiosis-elevated-oestrogen *Short chain fatty acids:* https://www.theendobellycoach.com/podcast/endometriosis-short-chain-fatty-acids https://www.theendobellycoach.com/podcast/endometriosis-propionate-acetate https://www.theendobellycoach.com/podcast/endometriosis-butyrate *Tools and treatments:* https://www.theendobellycoach.com/podcast/phgg-endo-belly-sibo-ibs https://www.theendobellycoach.com/podcast/endometriosis-ibs-psyllium-husk https://www.theendobellycoach.com/podcast/kiwis-for-constipation https://www.theendobellycoach.com/podcast/flax-chia-constipation **Need more help or want to learn how to work with me?** ***Ways to work with me:*** ⁠One to one coaching info and application⁠‍ ‍ [Endo Sessions: Single and mini-package one to one endo coaching](/endosessions) [SIBO Sessions: Single and mini-package one to one SIBO coaching](/sibosessions) [Live and Thrive with Endo 2.0 DIY online course](/live-thrive-with-endo) ⁠Masterclasses in endo nutrition, surgery prep and recovery and pain relief⁠ ⁠This EndoLife, It Starts with Breakfast digital cookbook⁠ **Affiliate Partnerships** mBIOTA -mBIOTA Elemental is the next generation of the elemental diet and is developed with leading gastroenterologists and food scientists. It’s both clinically effective and easy to drink. And for eligible United States customers, mBIOTA Elemental can be purchased with Health Savings Accounts (HSA) and Flexible Spending Accounts (FSA) funds. You can learn more about the formula at mbiota.com and get 20% off with code ENDOLIFE (all caps). Code is valid for the two-week protocol and until June 14th. Mira - Mira is an at-home hormone testing device for every day use. Use this link and code 2DUFFJESS20 to get 20% off the device and any future wand orders. Tempdrop- Track fertility effortlessly with Tempdrop’s Wearable Sensor. Get 15% off with code: ENDOLIFE ***Free resources:*** This podcast! ⁠Endometriosis Net Column⁠ ⁠Endometriosis News Column⁠ ⁠Substack ⁠ ⁠Instagram⁠

As I am still recovering from covid, today’s episode is a short bite sized episode looking at what the recent research is telling us about the endo belly and the gut microbiome of people with endo…

Spotify Apple Podcasts Amazon Music Website

Speakers: Jessica DuffinHost

Top entities: irritable bowel syndrome×12 endometriosis×3 Instagram×6 PubMed Central×4 National Center for Biotechnology Information

Show signals: SuitabilitySafeBiasNot politicalAudience≈15k followers

Endometriosis, IBS & GI Symptom Research3:39 – 5:35

Jessica DuffinHost

3:39

Okay, so first up, a 2023 study found that typically endometriosis patients who experience gastrointestinal symptoms report bloating, constipation, diarrhea, acid reflux, abdominal pain, pain with bowel movements, gas, nausea and vomiting.

Jessica DuffinHost

3:57

And a 2017 study looked at patients with IBS alone or IBS and endo, and found that pain during sex, pain that spreads to other areas and bowel symptoms that worsen around menstruation are more common in those with both conditions.

Jessica DuffinHost

4:14

So let's look further at the IBS piece and what the research is showing there.

Jessica DuffinHost

4:19

A 2022 systematic review and meta-analysis, and remember that that is a huge overview of all of the research.

Jessica DuffinHost

4:27

It's kind of the best data we have.

Jessica DuffinHost

4:30

This found that endopatients were three times more likely to have IBS than those without.

Jessica DuffinHost

4:36

Combined, around 23.4, so roughly 1 in 4, endometriosis patients also had IBS.

Jessica DuffinHost

4:43

And across the individual studies, the percentage of patients with endo and IBS varied from about 10.6 to 52%.

Jessica DuffinHost

4:51

Two other systematic reviews and meta-analyses from 2020 and 2021 also found a 2 to 3 fold risk of IBS in endo patients.

Jessica DuffinHost

5:03

Now, some may argue that these high IBS numbers are because many of us were misdiagnosed with IBS when we actually had endo.

Jessica DuffinHost

5:10

But, whilst it is common for people with endo to be misdiagnosed with IBS, a 2008 case-controlled study of 5,540 endo patients showed found that those with an existing endometriosis diagnosis were 2.5 times more likely of also receiving an IBS diagnosis in comparison to the control group.

Jessica DuffinHost

5:32

So this isn't a mistake.

Jessica DuffinHost

5:33

We have both.

irritable bowel syndromeEntityFunctional disorder
96%12 mentions
endometriosisEntityDisease
89%3 mentions
InstagramSoftware ApplicationSocial networking service
82%6 mentions
PubMed CentralWebsiteWeb site
75%4 mentions
National Center for Biotechnology InformationOrganization
68%1 mention
MDPICompanyCompany
61%1 mention
beta-glucuronidaseEntityProtein
54%1 mention
Small intestinal bacterial overgrowthEntitySyndrome
46%2 mentions
E. coliEntityBacteria
39%3 mentions
SubstackSoftware ApplicationWebsite
32%2 mentions
Flexible spending accountEntity
18%2 mentions
Health savings accountEntity
18%1 mention
United StatesCountryCountry in North America
18%1 mention
BacteroidotaEntityBacteria
4%1 mention

Medical ResearchHealth
Systematic ReviewsHealth > Medical Research
Meta-AnalysisHealth > Medical Research > Systematic Reviews
Estrogen LevelsHealth > Hormonal Health
Hormonal HealthHealth
Pain ManagementHealth
MicrobiomeHealth
Pelvic PainHealth > Pain Management > Chronic Pain
DysbiosisHealth > Microbiome > Gut Health
EndometriosisHealth > Medical Conditions
Medical ConditionsHealth
Chronic PainHealth > Pain Management
Gut HealthHealth > Microbiome
Health
Irritable Bowel SyndromeHealth > Medical Conditions > Endometriosis
SymptomsHealth > Medical Conditions > Endometriosis > Irritable Bowel Syndrome
FindingsHealth > Medical Research > Systematic Reviews > Meta-Analysis
Bacterial DiversityHealth > Microbiome > Gut Health > Dysbiosis
EndobellyHealth > Pain Management > Chronic Pain > Pelvic Pain
Gut RegulationHealth > Hormonal Health > Estrogen Levels
Nervous System InfluenceHealth > Hormonal Health > Estrogen Levels > Gut Regulation

Endometriosis, IBS & GI Symptom Research3:39 – 5:35

Jessica DuffinHost

3:39

Okay, so first up, a 2023 study found that typically endometriosis patients who experience gastrointestinal symptoms report bloating, constipation, diarrhea, acid reflux, abdominal pain, pain with bowel movements, gas, nausea and vomiting.

Jessica DuffinHost

3:57

And a 2017 study looked at patients with IBS alone or IBS and endo, and found that pain during sex, pain that spreads to other areas and bowel symptoms that worsen around menstruation are more common in those with both conditions.

Jessica DuffinHost

4:14

So let's look further at the IBS piece and what the research is showing there.

Jessica DuffinHost

4:19

A 2022 systematic review and meta-analysis, and remember that that is a huge overview of all of the research.

Jessica DuffinHost

4:27

It's kind of the best data we have.

Jessica DuffinHost

4:30

This found that endopatients were three times more likely to have IBS than those without.

Jessica DuffinHost

4:36

Combined, around 23.4, so roughly 1 in 4, endometriosis patients also had IBS.

Jessica DuffinHost

4:43

And across the individual studies, the percentage of patients with endo and IBS varied from about 10.6 to 52%.

Jessica DuffinHost

4:51

Two other systematic reviews and meta-analyses from 2020 and 2021 also found a 2 to 3 fold risk of IBS in endo patients.

Jessica DuffinHost

5:03

Now, some may argue that these high IBS numbers are because many of us were misdiagnosed with IBS when we actually had endo.

Jessica DuffinHost

5:10

But, whilst it is common for people with endo to be misdiagnosed with IBS, a 2008 case-controlled study of 5,540 endo patients showed found that those with an existing endometriosis diagnosis were 2.5 times more likely of also receiving an IBS diagnosis in comparison to the control group.

Jessica DuffinHost

5:32

So this isn't a mistake.

Jessica DuffinHost

5:33

We have both.

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