Trisomy 21 Transfer Gamble
A patient defied advice with remarkable outcome.
Norbert GleicherHost
David BaradHost
I'm the medical director and chief scientist here at the Center for Human Reproduction.

We have been here at the CHR transferring so-called chromosomally abnormal embryos.

Since 2014, we decided to start doing that as an experimental protocol with appropriate informed consent in collaboration with some other colleagues here in town for one simple reason, because we believed that testing embryos for chromosomal abnormalities was a lousy test, and we believed that a lot of the embryos that this test ultimately described as chromosomal abnormal were really not chromosomal abnormal.

In other words, that the test that was used had a lot of false positive results.

And as a consequence, we didn't use them frequently, even throughout embryos with good pregnancy potential.

How else could you prove it? Our arguments were not very well received by many of our colleagues at the time.

I'm the medical director and chief scientist here at the Center for Human Reproduction.

We have been here at the CHR transferring so-called chromosomally abnormal embryos.

Since 2014, we decided to start doing that as an experimental protocol with appropriate informed consent in collaboration with some other colleagues here in town for one simple reason, because we believed that testing embryos for chromosomal abnormalities was a lousy test, and we believed that a lot of the embryos that this test ultimately described as chromosomal abnormal were really not chromosomal abnormal.

In other words, that the test that was used had a lot of false positive results.

And as a consequence, we didn't use them frequently, even throughout embryos with good pregnancy potential.

How else could you prove it? Our arguments were not very well received by many of our colleagues at the time.
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Trisomy 21 Transfer Gamble
A patient defied advice with remarkable outcome.
Crowd-Stunning Conference Reveal
Then came a conference no one expected.
Embryos That Self-Correct
But how could abnormalities correct themselves biologically?
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