Can GLP-1s help with perimenopause and menopause? In this live conversation, I'm joined by Dr. Pat Taylor, a board-certified family physician specializing in obesity, menopause and metabolic medicine, to talk about GLP-1 therapy, microdosing, menopause and metabolic health.
Perimenopause can start as early as your mid-30s, and the hormonal shifts can bring belly weight gain, insulin resistance, mood changes and more, even when nothing else in your routine has changed. We explain what's happening, how GLP-1s and menopausal hormone therapy may work together, what microdosing means, and who may or may not be a good candidate, plus live Q&A.
**In this episode:**
- When perimenopause starts and common symptoms
- Estrogen, mood and the brain
- Why weight shifts to your midsection
- Insulin resistance and the labs to check
- Surgical menopause and testosterone
- Why GLP-1s may work differently in menopause
- Hormone therapy plus GLP-1s, and tirzepatide and hot flashes
- What GLP-1 microdosing really means, and who is (and isn't) a good candidate
- Maintenance without BMI cutoffs
**Chapters**
00:00 Welcome: microdosing and menopause
01:00 Perimenopause starts earlier than you think
03:00 Meet Dr. Pat Taylor
04:03 When perimenopause starts and common symptoms
06:01 Estrogen, mood and the brain
07:05 Why weight shifts to your midsection
08:02 Insulin resistance in perimenopause
09:04 Labs to check for insulin resistance
11:01 Visceral fat and health risks
12:01 Surgical menopause and testosterone
14:03 Why GLP-1s may work differently in menopause
16:00 Estrogen, your cycle and GLP-1 response
17:03 Hormone therapy plus GLP-1s
20:01 Tirzepatide and hot flashes
21:01 Q&A: itchy skin and ears
23:00 Prediabetes, diabetes and your chart
26:06 Diabetes medications and longevity
27:00 BMI and insurance coverage
30:04 Why Dr. Pat joined Belle
31:01 Belle launches GLP-1 microdosing
33:01 Food noise and mental capacity
34:03 Two pathways to start microdosing
36:00 What microdosing really means
39:02 Who's a good candidate for microdosing
43:03 Why menopausal hormone therapy matters
44:04 Who's not a good candidate
47:01 Maintenance with no BMI gates
50:01 How to join the microdosing program
52:06 Q&A: HRT timing and starting doses
54:05 Tirzepatide with B6
55:05 Wrap-up
**Learn more about Belle's microdosing program:** microdose.joinbelle.com
**Interested in GLP-1s, peptides, hormones and metabolic health? Start here:**
link.joinbelle.com/betterliving (coupon code BELLE15)
You'll find information on eligibility, available programs and next steps.
**Follow The Better Living PA** so you don't miss new episodes on GLP-1 medications, peptides, perimenopause and menopause, weight loss, metabolic health and healthy aging.
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*Medical disclaimer: The information shared on this podcast is for educational and informational purposes only and should not be considered medical advice. Listening to or watching these episodes does not create a provider-patient relationship. Always consult with your own qualified healthcare provider before starting, stopping, or changing any medication, supplement, peptide, treatment plan, or healthcare regimen.*