Sage Clinical Medicine & Research
Sep 4, 2026 · 7 min · 5 segments
Read the issue here: https://journals.sagepub.com/toc/hvsa/3/3
So the issue that we feature today in the journal focuses on recent advances on multiomics research that integrates genomics, transcriptomics, proteomics, and metabolomics to map the molecular mechanism of valvular heart disease like calcificotic stenosis and mitoregradation.
So we have previously published in the journal some articles related to this topic, including an excellent state-of-the-art review article by Scott Patterson and colleagues on extracellular matrix remodeling in aortic valve stenosis.
And actually, this previous article was published in the very first issue of the journal.
So there is currently no pharmacological treatment for valvular disease, as you know, and multi-omics research really has the potential to reveal novel therapeutic targets for aortic stenosis and mitral regurgitation.
So this focused issue therefore features two original research articles and two state-of-the-art articles.
most of them related to this important and timely topic that could pave the way for future pharmacotherapy in valvular disease.
So the issue that we feature today in the journal focuses on recent advances on multiomics research that integrates genomics, transcriptomics, proteomics, and metabolomics to map the molecular mechanism of valvular heart disease like calcificotic stenosis and mitoregradation.
So we have previously published in the journal some articles related to this topic, including an excellent state-of-the-art review article by Scott Patterson and colleagues on extracellular matrix remodeling in aortic valve stenosis.
And actually, this previous article was published in the very first issue of the journal.
So there is currently no pharmacological treatment for valvular disease, as you know, and multi-omics research really has the potential to reveal novel therapeutic targets for aortic stenosis and mitral regurgitation.
So this focused issue therefore features two original research articles and two state-of-the-art articles.
most of them related to this important and timely topic that could pave the way for future pharmacotherapy in valvular disease.
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