Sep 15, 2026 · 20 min · 10 segments
September is IC Awareness Month, and I’m back with Part 3 of my four-part series all about interstitial cystitis. In this episode, we’re talking about one of the most important pieces of my own…
Callie KrajcirHost
Your brain and nervous system are involved in creating all of the sensations you experience in your body.

So when we talk about neuroplastic symptoms, we're talking about a biological process involving the brain and nervous system.

Something gets injured, the injured part of the body sends a pain signal to the brain, and you feel pain.

Your brain is actively involved in creating the experience of pain based on information coming from your body and things like context, previous experiences, expectations, attention, emotions, and how much danger your brain believes you're in.

If you put your hand on a hot stove, we want your nervous system to create pain.

But imagine your smoke detector becomes so sensitive that every time you make toast, the alarm starts screaming.

Your nervous system is genuinely producing that alarm, but the presence of the alarm doesn't necessarily mean the house is burning down.

Your nervous system can learn to become extremely protective around certain sensations, activities, foods, situations, or parts of your body, and this is where the word neuroplastic comes in.

Your brain and nervous system are involved in creating all of the sensations you experience in your body.

So when we talk about neuroplastic symptoms, we're talking about a biological process involving the brain and nervous system.

Something gets injured, the injured part of the body sends a pain signal to the brain, and you feel pain.

Your brain is actively involved in creating the experience of pain based on information coming from your body and things like context, previous experiences, expectations, attention, emotions, and how much danger your brain believes you're in.

If you put your hand on a hot stove, we want your nervous system to create pain.

But imagine your smoke detector becomes so sensitive that every time you make toast, the alarm starts screaming.

Your nervous system is genuinely producing that alarm, but the presence of the alarm doesn't necessarily mean the house is burning down.

Your nervous system can learn to become extremely protective around certain sensations, activities, foods, situations, or parts of your body, and this is where the word neuroplastic comes in.
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