GLP-1 Hub: Support, Community, and Weight Loss
Jul 30, 2026 · 46 min · 15 segments
Send us Fan Mail Tara Rothenhoefer was one of the earliest participants in a tirzepatide clinical trial, before the medication had a brand name…
Tara RothenhoeferGuestAna ReisdorfHost
So she, you know, she was very much aware that I'm probably not gonna go out and start running today, or even this week, or maybe not even this month or year, but she said, like, "As soon as you feel like you're able, do something."
She was in the very first tirzepatide trial, back before the drug even had a name.
18 months and 132 pounds later, the trial ended and they sent her home with no medication, no follow-up, and no idea what came next.
Today, I'm talking with Tara Rothenhoefer, who fought obesity for 35 years, lost her older sister to complications from it, and became one of the first everyday faces of this medication in the national media.
We get into the exact moment the food noise went quiet, what happened to her body during the year she had no access to the medication, and the point where losing more weight stopped being a good thing.
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So she, you know, she was very much aware that I'm probably not gonna go out and start running today, or even this week, or maybe not even this month or year, but she said, like, "As soon as you feel like you're able, do something."
She was in the very first tirzepatide trial, back before the drug even had a name.
18 months and 132 pounds later, the trial ended and they sent her home with no medication, no follow-up, and no idea what came next.
Today, I'm talking with Tara Rothenhoefer, who fought obesity for 35 years, lost her older sister to complications from it, and became one of the first everyday faces of this medication in the national media.
We get into the exact moment the food noise went quiet, what happened to her body during the year she had no access to the medication, and the point where losing more weight stopped being a good thing.