Jun 3, 2026 · 8 min · 8 segments
Toxicities related to antibody-drug conjugates (ADCs) can significantly impact quality of life for patients with locally advanced or metastatic bladder cancer, but data-driven programs can help…
Cindy Y. JiangGuestSummer JohnsonHostShe's here to discuss how her institution designed algorithms to manage adverse events with these treatments.
To start, when did MD Anderson first begin administering this combination treatment?
Yeah, so we first started administering it more regularly once this combination of infortimapidotin and pembrolizumab was officially FDA approved now more than two, three years ago.
And so when we first started, we were still learning a lot about how to administer these drugs together.
And that became a big area of interest for the group because we noticed that there were patients that were developing more severe toxicities requiring hospitalization.
So we wanted to go about how to minimize or reduce the higher grade toxicities we were seeing.
She's here to discuss how her institution designed algorithms to manage adverse events with these treatments.
To start, when did MD Anderson first begin administering this combination treatment?
Yeah, so we first started administering it more regularly once this combination of infortimapidotin and pembrolizumab was officially FDA approved now more than two, three years ago.
And so when we first started, we were still learning a lot about how to administer these drugs together.
And that became a big area of interest for the group because we noticed that there were patients that were developing more severe toxicities requiring hospitalization.
So we wanted to go about how to minimize or reduce the higher grade toxicities we were seeing.
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