And Dr. Li, when you're starting these treatments, what endpoints do you use to decide when a patient's achieved their goal? And we can maybe dial back the therapy.

Okay.

And I'll address the first one is how do you gauge? Second one is a separate issue.

That is how you dial back.

All right.

So I would say... weight management ultimate goal is for better health.

I would work with each individual patient to really get to the point you have lost enough weight, but not in any way for you to be in a less functional state.

So we're wondering, with starting at GLP-1, could that help restore his mobility in the long run by taking some weight off, or would it maybe worsen his mobility through sarcopenia?