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Wesley K Lefferts
Researcher
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APPEARANCES
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Oct 7, 2026
Identifying how menopause impacts risk of stroke and dementia
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14:50Wesley LeffertsGUEST
So lot of people don't necessarily think of the large arteries as being directly related to brain health, but, um, the large arteries being the aorta, which is kind of the main pipe that comes off the heart, and then, uh, the first two parts of the carotid artery that go up to the brain are really actually critical in determining how blood flow actually kind of gets transmitted to the brain.
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15:08Wesley LeffertsGUEST
Um, the heart inherently just beats discontinuously, right? Where there's a contraction, blood flow comes out, and then it stops while the heart relaxes.
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15:16Wesley LeffertsGUEST
As you might imagine, if you're an end organ like the brain, you don't want discontinuous blood flow.
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15:22Wesley LeffertsGUEST
Um, and it turns out that the health and function of those large arteries is really critical in converting that discontinuous blood flow that's generated by the heart, but converting it into more continuous blood flow by the time it gets to those sensitive small vessels within the brain.
11 MINS LATER