Now, do the ramifications of PMOS or honestly metabolic dysfunction generally, do those vary by ethnicity at all?

Yeah, this is the interesting bit that the Rotterdam criteria and everything that was done around diagnosing PCOS, and I'll flip back to the old name, is that it was based on mainly European studies and collections of data done across Europe.

So typically Caucasian or Eastern European people diagnosed.

And that meant that the diagnostic criteria, which is the irregular periods, excess hair or acne, and then potential cysts on a scan, were derived from that cohort.

We know that PMOS shows up very differently in South Asian women.

They actually present, as you've already highlighted here, they present with insulin resistance at a much lower BMI.

Ah.

Tell us more.