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Scott Scher
Dr. Scott Sherr is a board-certified internal medicine physician in Boulder, CO, specializing in hyperbaric oxygen therapy (HBOT) and Health Optimization Medicine (HOMe).
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Aug 19, 2026
The Sympathetic Spiral of Doom: Why So Many Patients Stay Stuck
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4:25Scott ScherGUEST
Yeah, and this pattern specifically, there's two major aspects of it, right? So when you have, just to go back to the trauma example, you have somebody that is chronically stuck in fight or flight, right? They've had trauma as a child or as an adult or whatever.
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4:39Scott ScherGUEST
They're always in sympathetic mode, okay? If you're in sympathetic mode all the time, you do these things to the system constantly, like produce tons of cortisol, tons of neurotransmitters like norepinephrine and epinephrine, on a regular basis.
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4:53Scott ScherGUEST
And what this does over time is significantly dysregulates the system in multiple different ways.
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5:00Scott ScherGUEST
But how does it actually do that? It does it by dysregulating mitochondrial function.
28 MINS LATER

Rob LutzHOST
But can you give an example from your clinical practice where sequencing completely changed the outcome?