Okay.

And in terms of social determinants, particularly poverty, we know that SLE is a longstanding disease.

And in low to middle income countries, we understand that medical expenditures are largely out of pocket.

There is no minimal or very, very limited health insurance.

So what's the result? Patients would rather spend their income on basic food and shelter than their health.

Another social determinant would be education.

Per se, in low to middle income countries, we know that education is a luxury in LMICs.

So these