What are your thoughts there?

It's a great question, and it's something that I think about very often.

To get some perspective, to step back a little bit, Richard Nixon signed the National Cancer Act a little more than 50 years ago, four years ago.

To think what has happened in the last half century is nothing short of miraculous.

Cancer has been around for as long as humans have recognized it as a disease.

But what the power of science and investment in science and research has produced in the last half century is simply astonishing.

So before going to answer some of this, I do just want to remind the audience the importance of research and investment in research that the incredible advances we see are not, we didn't just stumble upon them, right? It's not just something that just happened by accident.

To you, in the next let's say five to ten years, what do you think are maybe just two or three of the most exciting? Maybe it's classes of therapeutics or maybe it's AI or the direction oncology is going, but what are you most bullish on? What makes you most excited?