about how we can use this test both as a one-off measurement and how we need to consider it in the context of other physiological covariates, if you like, as opposed to how we monitor it over time.

Yeah, so that's, I think it's a really important point to the difference between an individual measurement and trending over time.

And as a laboratory, maybe I'll back up just one quick step in terms of when a physician or a patient gets a result, the lab generally flags it as abnormal or normal.

And that doesn't really give you all the information.

It's not just either abnormal or normal.

We spend a lot of time in the lab trying to pick these cutoffs and identify what's normal, what's abnormal.

And the way we look at this really is by population base.

If this is how neurofilament is being used, how specific is NFL in this context for this particular problem of identifying eurilapse biology? Are there any problems in using the test in this way?