Renuga Vivekanandan
2
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Oct 8, 2026
#28, S2 The Pleural Infection Playbook
47:18
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Renuga VivekanandanGUEST
... um, but there's caveat, right? Leukocytosis can also be stress and other reasons, too.

Renuga VivekanandanGUEST
So just keeping an eye on, like, is it ba- um, neutrophil predominant? Is there bandemia? A lot of times i- in the ID world, we love to look at CBC with differentials.

Sameer AvasaralaHOST
So what's one principle that you wish every team understood about managing a pleural space infection?
#28, S2 The Pleural Infection Playbook
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49:30

Sameer AvasaralaHOST
What's going on through your head about microbiology, antibiotic selection, and things like that?

Renuga VivekanandanGUEST
So I always think about, like, is it loculated fluid, is it empyema? And a lot of times definitely sending for aerobic and anaerobic cultures are gonna be important, so I keep an eye on those.

Renuga VivekanandanGUEST
And we go, you know, talk with the microbiology team and making sure, like, what do you see, right? So those are the work that we are doing behind.

Renuga VivekanandanGUEST
But for myself, um, you know, I always teach my fellows it's really important to cover for anaerobes too.

Renuga VivekanandanGUEST
So a lot of times, okay, MRSA is growing, we're just gonna focus on MRSA, but you all know when you drain the fluid, put it on a Petri dish, you're exposing it to air, a lot of times you're gonna g- anaerobes are not gonna grow.

Renuga VivekanandanGUEST
So I make sure that we're covering if it's loculated, complicated, you're covering for the organism, but also for anaerobes.
39 MINS LATER

Sameer AvasaralaHOST
So what's one principle that you wish every team understood about managing a pleural space infection?