And she's asking, could the authors elaborate on the scientific rationale for using the more biologically precise terms HPV detected and HPV not detected and stress how this terminology may also improve patient understanding and communication compared with the traditional HPV positive and HPV negative labels?

Thank you very much, Ezra.

This is one of the most relevant questions during this podcast.

The current terminology reflects a more accurate understanding of HPV natural history.

In 2025, IPVs release two manuscripts updating the terminology we should use regarding HPV infection and how to explain it to our patients and importantly to our colleagues.

A negative HPV test does not necessarily mean that the virus has been eradicated.

It may instead reflect viral latency, immune control, or a viral load below the threshold of detection.

Kuduz Lawal from Nigeria, he's asking, What practical counseling should we provide when patients ask about commercially available vaginal gels claiming to promote HPV clearance?