
Natasha Barthel
Dr. Annatasha (Tasha) Bartel, BVM&S, DACVAA, is a board-certified veterinary anesthesiologist and Chief Medical Officer of Small Animal at King Animal Hospital, and co-host of The Random Anesthesia Topic podcast.
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Sep 15, 2026
S2E5. - Evidence vs. Reality: Does the Literature Hold Up?
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Natasha BarthelGUEST
So evidence-based medicine, for the listeners who may not be terribly familiar with this, but it's essentially what you're trying to do is you're trying to get, like, high quality, mostly, like, prospective studies, blinded, randomized, controlled, blah, blah, blah, and they've been peer reviewed by a series of other experts, and they've gone through the rigmarole of publication.

Natasha BarthelGUEST
And you're supposed to use the evidence that we find in that literature to drive clinical decision-making.

Natasha BarthelGUEST
One of the limitations that we frequently encounter in veterinary medicine is that our study populations or our study groups within these papers are insanely low, right? Like, there are more than a handful of papers out there that are published with four to six, uh, you know, cats in a group.

Natasha BarthelGUEST
And, you know, it's the one paper on this topic, and we're all supposed to, you know, make these big extrapolations, uh, thereof.

Natasha BarthelGUEST
I sort of have this Barthel theory of veterinary literature in general, which is there's six different levels of what's considered, um, to be worthwhile in terms of knowledge, right? And evidence-based is meant to be the top of the pyramid, and at the bottom of the pyramid is basically experiential, right? So it's what you do day to day.

