Meredith Spindler
Neurologist at Penn Medicine, Professor of Clinical Neurology and Associate Clinical Director of the Parkinson's Disease and Movement Disorders Center, University of Pennsylvania.
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APPEARANCES
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PODCASTS
Sep 18, 2026
Meredith SpindlerGUEST
In early disease, first of all, as I already said, there may be a period where patients feel they don't need any medication at all.
Meredith SpindlerGUEST
Once a patient knows they would like medication and they're noticing impacts on their quality of life from their symptoms, I typically start with immediate release carbidopa levodopa.
Meredith SpindlerGUEST
And often because it's early in the disease, it lasts long enough that they can take three daily doses and not really notice any kicking in or wearing off of the doses.